Clinical evaluation of giomer- and resin-based fissure sealants on permanent molars affected by molar-incisor hypomineralization: a randomized clinical trial

Abstract

Background Molar-incisor hypomineralization (MIH) is a common condition among children that significantly increases the risk of caries. The objective of this research was to evaluate the clinical success of giomer- and conventional resin-based sealants applied on first permanent molars (FPMs) affected by MIH. Methods One-hundred FPMs with MIH which were indicated for non-invasive fissure sealant were selected in 39 children, aged 6–12 years. Using a split mouth design, the FPMs were randomized into two groups; Group 1. Resin sealant (etch-and-rinse + Conceal F) and Group 2. Giomer sealant (self-etch primer + BeautiSealant). Clinical evaluation was performed using the modified United States Public Health Service (USPHS) criteria at 1, 3, 6 and 12 months. The Log-rank, Fisher’s exact test and Kaplan–Meier analysis were used for statistical analysis. Results At 12 months, the retention rates in Group 1 and Group 2 were 68% and %8, respectively (p = 0.000). The cumulative survival rates of conventional resin sealants were significantly higher than giomer sealants for all follow-up visits (p < 0.05). In Groups 1 and 2, the distribution of unsuccessful sealants on mandibular vs maxillary FPMs were 32.1% vs 31.8% (p = 0.612) and 91.7% vs 92.3% (p = 0.664), respectively. Although the success rate was higher for teeth with white opacities or lesions with less extension in Group 1, no significant difference was found. The average survival time was found as 10.46 ± 3.21 months in Group 1 and 4.02 ± 4.43 months in Group 2. Conclusions The conventional resin-based sealants yielded a better clinical performance over the 12-month evaluation period than the giomer sealants which were applied with self-etch primer. The high failure rate observed in giomer sealants could be explained by the possible deficiency in the etching capacity of self-etch primer on MIH-affected teeth. Trial registration ClinicalTrials.gov, NCT04929782. Registered 10 June 2021—Retrospectively registered, https://clinicaltrials.gov/ct2/show/NCT04929782.

Knowledge and perception regarding molar incisor hypomineralisation among dental students and dental hygienist students in Spain: a cross-sectional study

“…For molars, documented therapeutic options include infiltration of lesions with resins, glass ionomer or resin-modified glass ionomer restorations, preformed stainless steel crowns, and even planned extraction in severe cases for children aged 8 to 10 years, followed by orthodontic treatment. However, a recent randomized clinical trial [ 22 ] found that conventional resin-based sealants in permanent first molars have better long-term clinical performance than ionomer sealants with self-etch adhesive. This may be due to etching failure in teeth affected by MIH.…”

A concise review of dental sealants in caries management

“…Table 1 shows the retention rates of dental sealants published in the past ten years (2012–2022). For resin sealant, the retention rate ranges from 11% to 89% at a 6-month follow-up ( 40 , 52 , 61 , 62 ); from 18 to 88% at a 12-month follow-up ( 26 , 45 , 47 , 49 – 51 , 55 , 58 – 60 , 65 , 67 ); from 24% to 70% at an 18-month follow-up ( 54 , 57 , 68 ); from 21% to 80% at a 24-month follow-up ( 44 , 46 , 48 , 63 , 64 , 66 ). Studies with longer follow-up periods were limited.…”

“…Studies in other follow-up periods were limited. For hybrid sealant, the retention rates range from 8% to 26% at a 12-month follow-up ( 58 , 65 , 67 ). Studies with longer follow-up periods were limited.…”

Silver-modified atraumatic restorative treatment in managing early childhood caries. 1-year clinical results of “SMART” technique in primary teeth: A retrospective study

“…The teeth with Alpha and Bravo values are grouped in successful while the teeth with the value Charlie are divided into the group of unsuccessful cases [19]. The treated teeth were divided into groups according to the location (Mandibular-Maxillary) and the type of cavity (Class-1/Occlusal, Class-2, Class-3/Proximal).…”