2017
DOI: 10.5455/javar.2017.d209
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Clinical evaluation of ethanolic extract of curcumin (Curcuma longa) on wound healing in Black Bengal goats

Abstract: Objective: This study was aimed at clinical evaluation of surgical wound healing in goats treated with ethanolic extract of turmeric (Curcuma longa) rhizomes through topical route. Materials and methods: Eighteen surgical wounds were made in nine goats. The goats were divided into three groups; Group 1 (test group) was treated with ethanolic extract of turmeric, Group 2 (standard group) was treated with Povidone iodine, and the Group 3 was kept as untreated control. Follow up information was recorded from day … Show more

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Cited by 11 publications
(7 citation statements)
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“…These active compounds in turmeric rhizome (Curcuma domestica Val) are secondary metabolites that have antioxidant, antiinflammatory, antifungal, and antiviral effects. 7,8 One of the main keys that play a role in the wound closure process is fibroblasts which provide strength for wound contraction and unite the wound edges. (turmeric) can increase the proliferation of fibroblast cells.…”
Section: Discussionmentioning
confidence: 99%
“…These active compounds in turmeric rhizome (Curcuma domestica Val) are secondary metabolites that have antioxidant, antiinflammatory, antifungal, and antiviral effects. 7,8 One of the main keys that play a role in the wound closure process is fibroblasts which provide strength for wound contraction and unite the wound edges. (turmeric) can increase the proliferation of fibroblast cells.…”
Section: Discussionmentioning
confidence: 99%
“…Different types of bacteria, such as Staphylococcus spp., hemolytic Streptococci , and Pseudomonas spp . are mostly found in surgical wounds [ 16 ]. We have discovered the splendid antibacterial activity of both the marigold leaf paste and turmeric paste in wound healing in sheep, which is analogous to the findings of Nandita et al [ 24 ] and Dasgupta et al [ 25 ].…”
Section: Discussionmentioning
confidence: 99%
“…Moreover, marigold leaves might be more available than flowers in terms of quantity year-round. Miah et al [ 16 ] used turmeric in the wound healing of black Bengal goat and carried out antimicrobial tests and histological and morphological parameters. However, they did not compare the efficacy of turmeric with other herbal plants.…”
Section: Introductionmentioning
confidence: 99%
“…The rising preclinical data on curcumin’s medicinal disposition have endeared the interest of researchers both in academia and industry to the exploration of its potential clinical administration in the management of diverse disease conditions [ 42 , 48 , 56 , 66 ]. The potential of curcumin in wound care was evaluated using various models, including rats, and curcumin was shown to be instrumental in improving epithelialisation, fibroblast proliferation, vascular density, collagen deposition, and reorganisation [ 70 , 71 , 72 , 73 , 74 ]. This was demonstrated in a study by Mehrabani et al where curcumin was shown to foster wound healing by quenching free radicals and the subsequent modulation of inflammation through the inhibition of nuclear factor-B.…”
Section: Natural and Semi-synthetic Compounds For Wound Healingmentioning
confidence: 99%