2011
DOI: 10.1590/s0100-736x2011000900011
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Clinical evaluation of enalapril maleate and furosemide usage in dogs with degenerative myxomatous mitral valve, CHF functional class Ib

Abstract: 791Pesq. Vet. Bras. 31(9):791-797, setembro 2011 RESUMO.-[Avaliação clínica da utilização do maleato de enalapril e furosemida em cães com doença degenerativa mixomatosa da válvula mitral, classe funcional Ib.] A doença degenerativa mixomatosa da válvula mitral (DDMVM) é uma cardiopatia de alta incidência na clínica médica de pequenos animais, acometendo mormente cães idosos e raças de pequeno porte. Desta forma, foi realizada uma investigação científica objetivando avaliar clinicamente a utilização dos fár… Show more

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Cited by 4 publications
(5 citation statements)
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“…Thus, the results of this study confirm the variation in LA as MMVD progresses, corroborating the findings of Borgarelli et al (2008) and Franco et al (2011), who assessed LA-to-Ao ratio in dogs with MMVD and found that parameter to indicate the progression of such disease. However, we emphasize that the LA-to-Ao ratio refers to subjective values which might fluctuate in accordance with the technique used for its calculation.…”
Section: Discussionsupporting
confidence: 89%
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“…Thus, the results of this study confirm the variation in LA as MMVD progresses, corroborating the findings of Borgarelli et al (2008) and Franco et al (2011), who assessed LA-to-Ao ratio in dogs with MMVD and found that parameter to indicate the progression of such disease. However, we emphasize that the LA-to-Ao ratio refers to subjective values which might fluctuate in accordance with the technique used for its calculation.…”
Section: Discussionsupporting
confidence: 89%
“…In dogs with MMVD, the conventional assessment of LA, which includes the calculation of LA-to-Ao ratio using either two-dimensional or M-Mode echocardiography, allows a subjective differentiation among CHF functional classes (Franco et al 2011, Prada et al 2012. In turn, measuring LA volume and area through the method indicated in this study allows a more precise assessment of LA overload in dogs with MMVD, as it calculates the area and volume of the left atrial chamber.…”
Section: Discussionmentioning
confidence: 99%
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“…This is controversial, as we were expecting a lowered ACE plasma concentration with enalapril. Enalapril is reported to inhibit the production of ACEs and, thus, lower the ace plasma concentration (Franco et al 2011). A study performed previously by Sleeper et.…”
Section: Discussionmentioning
confidence: 92%
“…Zudem waren die Behandlungszeiträume in diesen Studien zum Teil deutlich länger als in der vorliegenden Arbeit (Yusuf et al 1991, Fox und E 2003, Ferrari et al 2006. Dagegen beruhen Studien, die die Wirksamkeit von ACE-Hemmern mittels Ultraschalluntersuchungen bei Menschen, Hunden und Pferden über-prüften, auf ähnlichen Patientenzahlen, wie in der hier vorgestellten Studie (Vieth 2001, Vinereanu et al 2001, Franco et al 2011, Kohkayasit und Surachetpong 2013 …”
Section: Therapieeffekt Auf Die Gewebedopplermessungenunclassified