Clinical evaluation of Desflurane versus Sevoflurane in laparoscopic surgery

Abstract

Aims and Objectives:The present study was undertaken to evaluate desflurane in terms of hemodynamic stability, recovery profile and perioperative complications and compare results of desflurane with routinely used sevoflurane for laparoscopic surgery. Methods: Eighty patients of either sex, scheduled for laparoscopic surgeries under general anaesthesia were randomly allocated into two groups i.e. Group D and Group S. Patients of Group D received desflurane and of Group S received sevoflurane as an inhalational anesthetic. The intraoperative haemodynamic parameters, recovery characteristics and postoperative complications were observed and compared between two groups. Results: Intraoperative MAP and HR did not differ between the two groups (P > 0.05). Desflurane led to faster early recovery but the intermediate recovery was similar in both the groups. The incidence of postoperative complications was comparable in both the groups but incidence of coughing was more in desflurane group which was self limiting. Conclusion: Desflurane can be used as an effective alternative to sevoflurane for maintenance of anaesthesia in laparoscopic procedures.