Clinical, electrophysiological subtypes and antiganglioside antibodies in childhood Guillain-Barré syndrome

Kannan, Meena A; Kishore, Rathna; Jabeen, Shaik Afshan; Mridula, Kandadai Rukmini; Rao, P Srinivasa; Borgohain, Rupam

doi:10.4103/0028-3886.86549

Cited by 38 publications

(42 citation statements)

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“…33 (66%) which was comparable to Sarkar et al (58.3%) but higher than meena et al(48.8%). [9,10] Again the incidence of URTI in the study (30%) is comparable to that of Sarkar et al (25.3%) and Meena et al (25.6%).The incidence of diarrhea in the presence study was 20%. However, incidences of diarrhea in Sarkar et al was 12% which is lower than the present study and 30.2% in Meena et al which was higher.…”

Section: Discussionsupporting

confidence: 77%

“…However, incidences of diarrhea in Sarkar et al was 12% which is lower than the present study and 30.2% in Meena et al which was higher. [9,10] The present study was done in western region of country while sarker et al and meena et al were done in east & south region respectively. The incidence of paresthesia and pain in this study was 68%which was lower than Sarkar et al (89%) & higher than Meena et al (41.8%).…”

Section: Discussionmentioning

confidence: 99%

“…[9,10] The lower mean age of presentation due to variation in infectious agent and its disease epidemiology according to region. There was history of antecedent illness in majority of patients ie.…”

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

To Study The Indicators For Severe Course of Guillain- Barre Syndrome

Shah¹,

Vohra²,

Rathod³

2017

Ann. Int. Med. Den. Res.

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Section: Discussionsupporting

confidence: 77%

Section: Discussionmentioning

confidence: 99%

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To Study The Indicators For Severe Course of Guillain- Barre Syndrome

Shah¹,

Vohra²,

Rathod³

2017

Ann. Int. Med. Den. Res.

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“…The variables included were; age, sex, city of life, month, season and year of involvement, the outcome after 60 days. All patients have gone under diagnostic and therapeutic managements [5]. The Guillain-Barre syndrome patients examined and managed by neurologist.…”

Section: Methodsmentioning

confidence: 99%

Study of acute flaccid paralysis surveillance system in Kerman (Iran) for one decade

Ebrahimi¹,

Nakhaee²,

Zahmatkesh³

et al. 2014

RusOMJ

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Background -During the past decade, polio eradication has stalled globally. Acute flaccid paralysis (AFP) surveillance is a key strategy for monitoring the progress of polio eradication. All AFP patients who referred to expert committee were evaluated about the causes. Methods -This case series study is the result of activities for one decade of expert AFP committee of Kerman University of Medical Sciences from 2002-2011, with coverage of more than 2,650,000 populations and 730,677 child with age of ≤15 years old. All patients have gone under diagnostic and therapeutic managements. Results -The total cases referred to Kerman expert committee of AFP for ten years were 147 cases. In our study the incidence of AFP was 2.016 per 100000 populations for one year.The most common causes of AFP were Guillain-Barre syndrome (GBS). Other causes of AFP were; stroke, synovitis, myelitis, seizures, cerebral palsy, viral infections, tumors, cerebellitis and non-polio AFP. The rate of GBS in our study was 0.96 per 100000 in children 15 years old or smaller, and more in male. In this study the incidence rate in cities with low mean temperature was higher than in cities with high mean temperature. Conclusion -We had no polio case in this period. The most common cause of AFPs was Guillain-Barre syndrome. The incidence of GBS was higher in areas with low mean temperature.

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“…Although GBS is a serious disease, recovery is the rule in children with very low morbidity and mortality [7]. It is always complete, without any significant difference in the duration of recovery [8]. Poor prognostic factors are related to the presence of severe disability on admission, cranial nerve affection, the need for mechanical ventilator and electrophysiological types (axonal form) [9,10].…”

Section: Introductionmentioning

confidence: 99%

Assessment of New Strategies in the Management of Guillain Barre Syndrome: Cairo University

Rady¹,

Attala²

2014

JPNC

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The treatment of GBS consists of both supportive and immunomodulatory treatments, among which intravenous immunoglobulin (IVIG) and plasma exchange (PE) are considered most effective [11]. The majority of children achieving a complete functional recovery within 6 months from the onset of illness AbstractBackground: Guillain Barre Syndrome (GBS) deserves a serious attention in children. The treatment of GBS consists of both supportive and immune-modulator treatments, among which intravenous immunoglobulin (IVIG) and plasma exchange (PE) are considered most effective. We aimed to assess the outcome of new strategies in the management of moderate to severe cases.Methodology: This is a retrospective study including 38 GBS children, divided into 3 groups. Group I (30 children) received concomitant therapy of intravenous steroid with IVIG, group II (5 children) received 2 courses, 2 weeks apart, of IVIG (0.4 g/kg/ day) over 5 days each, and group III (3 children) received 2 courses of PE, 5 sessions each, 2 weeks apart.Results: Death occurred only among cases of group I (10/20 cases) 33.3%. Children in group I showed regressive course (p= 0.01). Higher incidence of mechanical ventilation was found in group II (66.6%). Cases in group II stayed longer (median=77days) than those in group I or III. Conclusion:The combination of IVIG and intravenous steroid can be used to hasten recovery in moderate GBS. The use of 10 sessions of PE can decrease the need for mechanical ventilation. Bulbar affection upon admission can be considered as a sign of severity.

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Clinical, electrophysiological subtypes and antiganglioside antibodies in childhood Guillain-Barré syndrome

Abstract: In this study, AMAN subtype accounted for a significant proportion of pediatric GBS. AMAN was associated with diarrhea and specific antiganglioside antibodies. Recovery in children with GBS was complete, irrespective of the subtype.

Cited by 38 publications

References 0 publications

To Study The Indicators For Severe Course of Guillain- Barre Syndrome

To Study The Indicators For Severe Course of Guillain- Barre Syndrome

Study of acute flaccid paralysis surveillance system in Kerman (Iran) for one decade

Assessment of New Strategies in the Management of Guillain Barre Syndrome: Cairo University

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