Clinical Electromyography

Effect of acetyl-l-carnitine in the treatment of diabetic peripheral neuropathy: A systematic review and meta-analysis

“…Both these parameters are affected by the state of the myelination of the nerve. [31] Reduction of amplitudes of recorded responses generally indicates a loss of axons. [31] The conduction velocity also depends on the state of myelination and is often decreased in disorders affecting nerve myelination, although it could be normal if a few myelinated axons remain intact.…”

“…[31] The conduction velocity also depends on the state of myelination and is often decreased in disorders affecting nerve myelination, although it could be normal if a few myelinated axons remain intact. [31] From a molecular point of view, ALC seems to able to enhance the expression of NGF and its receptors, increases the regeneration of the nerve reducing the myelinic degeneration and finally improves the anatomy and physiology of the nerve. [8,14,32] All these factors probably contributed to the effect of ALC on EMG parameters.…”

Muscular dystrophies and related skeletal muscle disorders in an Indian population – a prospective correlative study

“…Needle EMG was done in at least two proximal muscles of affected limbs and findings classified into myopathic, neurogenic or mixed. 8 Muscle biopsy from a moderately affected proximal muscle was performed under local anesthesia in all patients, and a 1-2 cm long specimen with a diameter of approximately 1 cm was collected from all patients and immediately transported in a sterile container to the neuropathology laboratory for sectioning and preparation of slides. After freezing of tissue, all slides were subjected to hematoxylin-eosin staining and all slides suggestive of features of muscular dystrophy (variation in fiber size, fiber splitting, necrosis, regeneration, moth eaten fibers, ring fibers) were further subjected to staining with immunohistochemical stains for dystrophin 1, 2 and 3; adhalin; emerin and merosin.…”

A voltammetric sensor based on graphene-modified electrode for the determination of trace amounts of l-dopa in mouse brain extract and pharmaceuticals

“…PD is believed to be related to low levels of dopamine in certain parts of the brain [2]. Lack of dopamine supply will lose control over the basic movement patterns, such as walking, writing, and reaching for objects, and other basic programs cannot operate properly [3].…”