Clinical elastography

Sporea, Ioan

doi:10.11152/mu-1693

Cited by 4 publications

(2 citation statements)

References 6 publications

(9 reference statements)

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“…Elasticity imaging or elastography is an imaging modality based on tissue stiffness or hardness, rather than anatomy. US elastography can be considered the imaging equivalent of palpation, being able to quantify the stiffness of a lesion, which was previously judged only subjectively by physical examination[ 10 , 11 ]. Palpation has been used to evaluate malignancy for a very long time.…”

Section: Introductionmentioning

confidence: 99%

Comparison of resistive index and shear-wave elastography in the evaluation of chronic kidney allograft dysfunction

Jesrani,

Faiq,

Rashid

et al. 2024

World J Transplant

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BACKGROUND Detection of early chronic changes in the kidney allograft is important for timely intervention and long-term survival. Conventional and novel ultrasound-based investigations are being increasingly used for this purpose with variable results. AIM To compare the diagnostic performance of resistive index (RI) and shear wave elastography (SWE) in the diagnosis of chronic fibrosing changes of kidney allograft with histopathological results. METHODS This is a cross-sectional and comparative study. A total of 154 kidney transplant recipients were included in this study, which was conducted at the Departments of Transplantation and Radiology, Sindh Institute of Urology and Transplantation, Karachi, Pakistan, from August 2022 to February 2023. All consecutive patients with increased serum creatinine levels and reduced glomerular filtration rate (GFR) after three months of transplantation were enrolled in this study. SWE and RI were performed and the findings of these were evaluated against the kidney allograft biopsy results to determine their diagnostic utility. RESULTS The mean age of all patients was 35.32 ± 11.08 years. Among these, 126 (81.8%) were males and 28 (18.2%) were females. The mean serum creatinine in all patients was 2.86 ± 1.68 mg/dL and the mean estimated GFR was 35.38 ± 17.27 mL/min/1.73 m2. Kidney allograft biopsy results showed chronic changes in 55 (37.66%) biopsies. The sensitivity, specificity, positive predictive value (PPV), and negative predictive value (NPV) of SWE for the detection of chronic allograft damage were 93.10%, 96.87%%, 94.73%, and 95.87%, respectively, and the diagnostic accuracy was 95.45%. For RI, the sensitivity, specificity, PPV, and NPV were 76.92%, 83.33%, 70.17%, and 87.62%, respectively, and the diagnostic accuracy was 81.16%. CONCLUSION The results from this study show that SWE is more sensitive and specific as compared to RI in the evaluation of chronic allograft damage. It can be of great help during the routine follow-up of kidney transplant recipients for screening and early detection of chronic changes and selecting patients for allograft biopsy.

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Section: Introductionmentioning

confidence: 99%

Comparison of resistive index and shear-wave elastography in the evaluation of chronic kidney allograft dysfunction

Jesrani,

Faiq,

Rashid

et al. 2024

World J Transplant

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“…Физической основой метода эластографии является модуль Юнга -величина, характеризующая сопротивление ткани растяжению или сжатию при упругой деформации [37]. Методы ультразвуковой эластографии можно разделить на две категории: квазистатические, или основанные на деформации, и динамические, или основанные на сдвиговых волнах [38,39]. В компрессионной (квазистатической) эластографии используется прямая зависимость E = σ / ε (закон Гука), в которой σ -приложенное извне напряжение, а ε -деформация.…”

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Modern Ultrasound Methods of Studying the Biomechanical Properties of the Lens. Review

Sakalova¹,

Андреева²,

Al-Mahdar³

2021

Oftalʹmologiâ

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Cataract is one of the most common diseases in ophthalmology nowadays, ranks first in the world among the causes of reversible blindness and remains a multifactorial disease, involving complex interactions between metabolic disorders, genetic predisposition and environmental risk factors. Studying the properties of the lens is important in “cataract” surgery from a clinical perspective. Determination of the mechanical hardness of the lens is particularly important to optimize the amount of ultrasonic energy expended during phacoemulsification in order to minimize the number of complications, however, the existing methods are rather subjective and based mainly on biomicroscopy with visual assessment. Ultrasound constitutes a significant part of the methods of studying the lens. There are methods for determining the density of the lens using A-scan (one-dimensional image) and B-scan (two-dimensional image). Basically, these techniques provide information on acoustic density, but not on mechanical hardness. Several studies have used a high frequency needle tranducer to determine the hardness of the lens. The authors believe that the combination of an ultrasound needle tranducer and a phacoemulcification probe for real-time feedback may provide better surgical efficiency. Ultrasound elastography, static and dynamic is used to assess the elastic properties of tissues in many areas of medicine. In ophthalmology, elastography is not used in general clinical practice, however, the density of the lens is assessed in vivo using compression elastography in some studies. Also, a number of researchers offer combined system of ultrasound elastography and OCT, called OCTelastography. It is assumed that OCT elastography can provide better spatial image resolution and faster acquisition rates. The literature review reveals summarized data on methods of studying the lens, its acoustic and mechanical density, using various ultrasound research techniques, including such poorly understood methods in ophthalmology as compression elastography and optical coherent elastography.

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