Clinical efficacy of platelet-rich plasma in the treatment of lateral epicondylitis: a systematic review and meta-analysis of randomized placebo-controlled clinical trials

Nonoperative treatment of lateral epicondylitis: a systematic review and meta-analysis

“…Few prospective randomized trials have been published comparing PRP injections with placebo. The results of the present study are similar to a recently published systematic review and meta-analysis by Simental-Mendia et al 33 which reported comparable results between PRP and placebo in pain and functional scores. The present study found similar outcomes with the addition of one further study to the meta-analysis.…”

Ultrasound-Guided Procedures in Common Tendinopathies at the Elbow: From Image to Needle

“…Platelet-rich plasma is an autologous preparation from patients' blood that can enhance the healing process. Simental-Mendía et al [44] found no difference in improvement in pain and joint functionality comparing PRP with placebo (SS). Several meta-analyses compared PRP and CS injection effects.…”

Effects of Hypertonic Dextrose Injection (Prolotherapy) in Lateral Elbow Tendinosis: A Systematic Review and Meta-analysis

“…32 For inactive control, we defined as "no treatment", "standard care", or a "waiting list control", and these included watchful-waiting, bracing and usual care. For active control, we defined as the use of different injection solutions or a different kind of therapy, which included exercise, 8 manual therapy, 33 dry needling, 34 shock-wave, 10 laser, 11 injections of corticosteroids, 9 platelet rich plasma injection, 13 autologous whole blood injection, 14 and normal saline. 35…”

“…7 However, a recent review has shown that the magnitude of the effect is small compared with other passive interventions. 8 Other second-line interventions such as corticosteroid injections, 9 shock wave therapy, 10 laser therapy, 11 bracing, 12 and newer options such as platelet-rich plasma, 13 and autologous whole blood injection, 14 have been evaluated in many randomized trials but there is no definitive evidence or consensus on which should be considered as the priority in LET. 15,16 Hypertonic dextrose prolotherapy (DPT) is an injection therapy used to treat chronic painful musculoskeletal conditions.…”