Clinical Efficacy of a Traditional Ayurvedic Compound on Peyronie's Disease: A Case Study

Abstract

Peyronie's disease (PD) is an acquired benign disease of the penis. It is a localized connective tissue disorder, includes the presence of fibrous plaque in the penile shaft, penile curvature, penile pain and erectile dysfunction. There are numerous conventional oral drugs to treat the condition with weak scientific evidence. Due to lack of definite pathophysiology of the disease surgical therapy still represents the gold standard for correction of penile deviation. Phytomedicines and traditional medicines are the first choice to treat male sexual disorders in many developing countries. We report a case of a 45-year-old male who presented with plasticity of penis, difficulty of erection and sexual inability. We treated this case with Kanchanara Guggulu, a classical Ayurvedic formulation and got promising result in reduction in size of plaque, reduction of curvature of the penis, diminution in pain at erection, correction of erection function. Moreover, well structured, standardized, randomized placebo-controlled studies have to be done in future.