Clinical efficacy and adverse effects of weekly single dose leflunomide in refractory rheumatoid arthritis

Paul, BJ; Thachil, EJ; Jayachandran, NV; Radhakrishnan, Suma

doi:10.1016/s0973-3698(10)60020-9

Cited by 4 publications

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“…In the present study, an attempt has been made to assess the quality of life in both the old and new RA patients taking combination non-biologic DMARDs therapy. The gender wise distribution of Rheumatoid Arthritis in the present study is 87% female which is approximately same with the Indian scenario (84.5%, 88.6%) [26,27] as well as with the global data (86%, 80%). [21,28] The mean age of Rheumatoid Arthritis patients in the present study is 45.85 ± 9.54 years with the mean (± SD) age of onset of Rheumatoid Arthritis in patients is 41.48 ± 9.38 years.…”

Section: Discussionsupporting

confidence: 87%

Quality of Life in Rheumatoid Arthritis patients taking combination DMARDs

Singh¹

2017

jmscr

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Section: Discussionsupporting

confidence: 87%

Quality of Life in Rheumatoid Arthritis patients taking combination DMARDs

Singh¹

2017

jmscr

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Rheumatology science and practice in India

2018

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The practice of rheumatology in a country like India presents its own unique challenges, including the need to manage patients in a cost-constrained setting, where the lack of uniform government funding for healthcare merits the need to optimize the use of cheaper medicines, as well as devise innovative strategies to minimize the use of costlier drugs such as biologic disease-modifying agents. Use of immunosuppressive agents is also associated with increased risks of infectious complications, such as the reactivation of tuberculosis. In this narrative review, we provide a flavor of such challenges unique to Rheumatology practice in India, and review the published literature on the management of common rheumatic diseases from India. In addition, we critically review existing guidelines for the management of rheumatic diseases from this part of the world. We also discuss infectious etiologies of rheumatic complaints, such as leprosy, tuberculosis, and Chikungunya arthritis, which are often encountered here, and pose a diagnostic as well as therapeutic challenge for clinicians. There remains a need to identify and test more cost-effective strategies for Indian patients with rheumatic diseases, as well as the requirement for more government participation to enhance scant facilities for the treatment of such diseases as well as foster the development of healthcare services such as specialist nurses, occupational therapists and physiotherapists to enable better management of these conditions.

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Upadhyaya

2007

Indian Journal of Rheumatology

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Clinical efficacy and adverse effects of weekly single dose leflunomide in refractory rheumatoid arthritis

Cited by 4 publications

References 14 publications

Quality of Life in Rheumatoid Arthritis patients taking combination DMARDs

Quality of Life in Rheumatoid Arthritis patients taking combination DMARDs

Rheumatology science and practice in India

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