Clinical Effects of Personalized Dialysate Sodium in Conventional, Quotidian, and Nocturnal Home Hemodialysis Patients: A Randomized Crossover Trial

Thomson, Benjamin; Li, Lihua; Lindsay, Robert M.

doi:10.21767/2472-5056.100039

Cited by 1 publication

(2 citation statements)

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“…Various substances can be administered using the dialysate as a vehicle. Some patients have received short-term phosphate supplementation using dialysate that has been phosphate-enriched [21]. The FDA has given its blessing to a new iron supplement known as "ferric pyrophosphate citrate" for use as an iron-free alternative to be added to the dialysate in order to maintain haemoglobin levels in long-term HD patients.…”

Section: Future Developmentmentioning

confidence: 99%

“…The FDA has given its blessing to a new iron supplement known as "ferric pyrophosphate citrate" for use as an iron-free alternative to be added to the dialysate in order to maintain haemoglobin levels in long-term HD patients. Each HD treatment can include the administration of ferric pyrophosphate citrate, which keeps haemoglobin levels steady without raising iron reserves [21].…”

Section: Future Developmentmentioning

confidence: 99%

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Individualising / personalizing hemodialysate composition

Arya

Priya²,

Varghese

2022

ijhs

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The effectiveness of the haemodialysis (HD) treatment directly affects the survival and quality of life of dialysis patients. In this regard, the composition of the dialysate, including the quality of the water, is very important. Normalizing the plasma electrolyte and mineral concentrations before to dialysis while reducing significant changes in the patient's intradialytic plasma concentrations is one of HD's main goals. For the purpose of avoiding intra- and interdialytic hypotension as well as pulmonary edoema, adequate sodium (Na) and water elimination is essential. The cardiovascular system and the bones may be protected by having the right amounts of calcium (Ca) and magnesium (Mg) in the dialysate. This will help to avoid extraskeletal calcifications, severe secondary hyperparathyroidism, and adynamic bone disease. A steady pH in body fluids is required for proper protein and membrane function as well as bone protection, and this is achieved by maintaining an adequate bicarbonate concentration [HCO3]. A sufficient dialysate glucose concentration prevents life-threatening hypoglycemia and severe hyperglycemia, which can cause serious cardiovascular problems and exacerbate diabetic comorbidities.

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Section: Future Developmentmentioning

confidence: 99%

Section: Future Developmentmentioning

confidence: 99%