Clinical effectiveness of VIA and colposcopy based management of cervical intraepithelial neoplasia

Jesmin, Zannatul Ferdous; Khanam, Afroza; Saha, Eti; Hossain, Mokter

doi:10.3329/bmjk.v47i1-2.22557

Cited by 4 publications

(3 citation statements)

References 3 publications

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“…The colposcopic diagnosis of CIN requires an understanding and recognition of four main features-colour tone intensity of acetowhitening, margins and surface contour of acetowhite area, vascular pattern and iodine staining. Variations in quality and quantitity of these atypical appearances help in differentiating CIN from other lesions and between grades of CIN 22 .…”

Section: Resultmentioning

confidence: 99%

Colposcopic Evaluation of Visual Inspection with Acetic Acid Positive Cases of Unhealthy Cervix

Kasem¹,

Razzaque

Adiba

et al. 2019

J. Bangladesh Coll. Phys.

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Cervical cancer is the commonest form of cancer in women in virtually all developing countries1. It is the third most common cancer among women worldwide2. Almost 80% of cervical cancer occurs in developing countries. In developed nations, the figure for invasive cervical cancer are much lower due to adaptation of different screening tests1. All sexually active women are at risk of acquiring a Human Papilloma Virus (HPV) infection which may lead to cervical cancer in the future3. Cervical cancer is a preventable disease as the different screening, diagnostic and therapeutic procedures are effective. The screening procedures are VIA (Visual inspection of cervix with acetic acid), Pap’s smear and HPV DNA test. Colposcopy is the triage in screening, taking colpospoy directed biopsy as well as treatment of CIN such as cold coagulation, cryotherapy, and LEEP (Loop electro-surgical excision procedure)4. Objective: To study the role of Colposcopy in the evaluation VIA positive cases of unhealthy cervix, to localize the leisons to obtain the biopsies from the selected areas and detection of precancerous lesion of cervix for early management. Meterials and Methods: This was a prospective observational study done among 306 married women aged 18-65 years who had clinically unhealthy cervix attending the VIA and colposcopy clinic in Department of Obstetrics and Gynaecology of Sir Salimullah Medical College and Mitford Hospital from January 2015 to December 2016. All the patients were subjected to VIA test. Colposcopic evaluation done in VIA positive cases and the findings were noted. Colposcopy directed biopsy was taken from colposcopically suspected areas. Results: Out of 306 cases, 63 women had positive VIA tests and 233 women had negative VIA tests. Colposcopic evaluation were undertaken among 63 VIA positive cases. Colposcopy directed punch biopsy revealed that 28 (60.32%) cases had positive lesions like CIN or invasive carcinoma and 25 (39.68%) had neither CIN or invasive lesions . Among positive leisons about 30.16% had CINI, 1.59 % had CIN II, 0% had CIN III and 28.57% had invasive carcinoma. In this study sensitivity and specificity of colposcopy examination of VIA positive cases were found 94.74% and 56% respectively. Conclusion: It is evident that colposcopy plays a very important role in the evaluation of VIA positive cases of unhealthy cervix. So that early diagnosis and treatment of preinvasive and early invasive carcinoma of cervixis is possible. So wide use of colposcopy in screening program of Bangladesh speciallly in the VIA positive cases can reduce the many young women’s morbidity and mortality. J Bangladesh Coll Phys Surg 2019; 37(2): 60-65

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Section: Resultmentioning

confidence: 99%

Colposcopic Evaluation of Visual Inspection with Acetic Acid Positive Cases of Unhealthy Cervix

Kasem¹,

Razzaque

Adiba

et al. 2019

J. Bangladesh Coll. Phys.

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“…The colposcopic diagnosis of CIN requires an understanding and recognition of four main features: Color tone, intensity of acetowhitening, margins and surface contour of acetowhite area, vascular pattern, and iodine staining. Variations in quality and quantity of these atypical appearances help in differentiating CIN from other lesions and between grades of CIN [7] . In our study, 25.4% were between 20-29 years, 40.0% women were between 30-39 years, 23.1% women belonged to the age group of 40-49 years and 11.5% were between 50-60 years.…”

Section: Discussionmentioning

confidence: 99%

Correlation of colposcopic findings with biopsy in cervical cancer screening

Panwar¹,

Tyagi²,

Maheshwari³

2020

Int. J. Clin. Obstet. Gynaecol.

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Aim: to correlate the colposcopic findings with biopsy in cases of abnormal cervical cytology Materials and Methods: This was a prospective clinical study conducted among 300 women who fulfilled the selection criteria were conducted in the Department of Obstetrics and Gynaecology at Muzaffarnagar Medical College & Mahesh hospital from the November 2017 to November 2019. Patients who had pathological cervical appearance or Pap smear results of ASCUS, AGUS, LSIL or HSIL were referred to colposcopy. Results: Majority (40.0%) women were between 30-39 years of age group. Histopathology confirmed chronic cervicitis in 5 (9.1%) cases, 35 (63.6%) women with CIN I, 12 (21.8%) with CIN II, 3 (5.5%) with CIN III. The colposcopy and histopathology findings correlated in 90.9% cases. Conclusion: study demonstrated correlation between colposcopy and histology. Women with clinical diagnosis of unhealthy cervix should be evaluated by cytology to detect any premalignant or malignant lesions.

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“…Variations in quality and quantity of these atypical appearances help in differentiating CIN from other lesions and between grades of CIN. 21…”

Section: Discussionmentioning

confidence: 99%

Role of Colposcopy in the Evaluation of Visual Inspection of Cervix with Acetic Acid-positive Cases of Unhealthy Cervix

Begum¹,

Kasem²,

Razzaque³

et al. 2017

Journal of SAFOMS

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Introduction Cervical cancer is the second most common cancer in women worldwide, and it is the principal cancer of women in most developing countries, where 80% of cases occur. This disease is preventable by screening and treatment of preinvasive condition. All sexually active women are at risk of acquiring a human papillomavirus (HPV) infection that may lead to cervical cancer in the future. Cervical cancer is a preventable disease as the different screening, diagnostic, and therapeutic procedures are effective. The screening procedures are visual inspection of cervix with acetic acid (VIA), Pap smear, colposcopy, and HPV deoxyribonucleic acid test. Among them, colposcopy is effective in screening, taking colposcopy-directed biopsy as well as treatment of cervical intraepithelial neoplasia (CIN), such as cold coagulation, cryotherapy, and loop electro-surgical excision procedure. Hence, there is an obvious need to subject the women with VIA-positive report to colposcopy and directed biopsy. This study is done to evaluate the role of colposcopy in evaluation of VIA-positive cases. Objective Colposcopic evaluation of VIA-positive cases and detection of precancerous lesion of cervix for early management. Materials and methods This was a cross-sectional study done among married female patient aged 22 to 65 years, who had VIA-positive report, and attending the colposcopy clinic in the Department of Obstetrics and Gynecology of Sir Salimullah Medical College and Mitford Hospital from January 2014 to December 2016. Colposcopy-directed punch biopsy was taken from the abnormal colposcopic appearance and specimen sent for histopathological examination. Results Out of 97 cases, all had VIA-positive acetowhite areas. But colposcopy revealed that 76.29% had CIN and invasive lesions, while 23.71% had either normal or inflammatory lesions. Colposcopy-directed punch biopsy revealed that 59.79% cases had positive lesions like CIN or invasive carcinoma and 40.21% had neither CIN nor invasive lesions. Among positive lesions, about 34.02% had CIN I, 3.09% had CIN II, 0% had CIN III, and 22.68% had invasive carcinoma. In this study, sensitivity and specificity of colposcopy examination were found 94.83 and 51.28% respectively. Conclusion Cervical cancer presents as major cause of morbidity and mortality, especially in developing countries like Bangladesh. In developing countries, the various screening programs are implemented for its early detection and treatment. It is evident that colposcopy plays a very important role in early diagnosis and treatment of preinvasive and early invasive carcinoma of cervix. So wide use of colposcopy in screening program of Bangladesh can reduce many young women's morbidity and mortality. How to cite this article Kasem SB, Razzaque SA, Adiba R, Anika S, Begum F. Role of Colposcopy in the Evaluation of Visual Inspection of Cervix with Acetic Acid-positive Cases of Unhealthy Cervix. J South Asian Feder Menopause Soc 2017;5(2):102-106.

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Clinical effectiveness of VIA and colposcopy based management of cervical intraepithelial neoplasia

Abstract: Cervical cancer develops from early precancerous lesion known as cervical intraepithelial neoplasia (CIN).

Cited by 4 publications

References 3 publications

Colposcopic Evaluation of Visual Inspection with Acetic Acid Positive Cases of Unhealthy Cervix

Colposcopic Evaluation of Visual Inspection with Acetic Acid Positive Cases of Unhealthy Cervix

Correlation of colposcopic findings with biopsy in cervical cancer screening

Role of Colposcopy in the Evaluation of Visual Inspection of Cervix with Acetic Acid-positive Cases of Unhealthy Cervix

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