Clinical effectiveness of the sequential 4-channel NMES compared with that of the conventional 2-channel NMES for the treatment of dysphagia in a prospective double-blind randomized controlled study

Seo, Kyoung Ho; Jang, Joonyoung; Jang, Eun Gyeong; Park, Yulhyun; Lee, So Young; Kim, Bo Ryun; Park, Donghwi; Park, Sung Won; Hwang, Hyeoncheol; Kim, Nam Hun; Oh, Byung Mo; Seo, Han Gil; Lee, Jun Chang; Ryu, Ju Seok

doi:10.1186/s12984-021-00884-6

Cited by 5 publications

(7 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Moreover, in a recent randomized controlled study comparing rehabilitative effects of the sequential 4-channel NMES to the 2-channel NMES, the 4-channel NMES showed significant clinical improvement in penetration-aspiration scale and videofluoroscopic dysphagia scale scores. These results suggest that the sequential 4-channel NMES, through its activation of the suprahyoid, thyrohyoid, and other infrahyoid muscles mimics physiological activation patterns and may therefore be a new effective treatment for dysphagia 13 .…”

Section: Introductionmentioning

confidence: 77%

“…Therefore, a clearer understanding of how the sequential 4-channel NMES shows the rehabilitative effectiveness is needed. The aim of this study was to investigate the mechanism of the rehabilitative effects of the sequential 4-channel NMES using kinematic analysis of the hyoid bone movement, using data from a randomized controlled trial 13 . We hypothesized that the vertical and horizontal movement extents, as well as the duration of hyoid movements in the 4-channel NMES may be different from those in the 2-channel NMES.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Kinematic mechanism of the rehabilitative effect of 4-channel NMES: post-hoc analysis of a prospective randomized controlled study

Lim,

Lee,

Jang

et al. 2023

Sci Rep

Self Cite

View full text Add to dashboard Cite

The sequential 4-channel neuromuscular electrical stimulation (NMES), based on the normal contractile sequences of swallowing-related muscles, is a new rehabilitative treatment. The objective of this study was to explore the mechanism of the rehabilitative effect of the 4-channel NMES using kinematic analysis of videofluoroscopic swallowing study (VFSS) data. For this post-hoc analysis, we included a subset of participants from the prospective randomized controlled study on the clinical effectiveness of the sequential 4-channel NMES compared with that of the conventional 2-channel NMES. Seventeen subjects (11 and six in the 4- and 2-channel NMES groups, respectively) were eligible for the kinematic analysis of VFSS data. The hyoid bone movement was analyzed by evaluating the distance and time parameters with four peak points (A, B, C, D). The 4-channel NMES group showed significant improvement in vertical distances (A–C), horizontal distance (A–B, A–C), time interval (A–B–C) and total time, compared with their pretreatment data. The 2-channel NMES group showed significant improvements in time interval (A–B); however, the Euclidean distance (A–D) and mean velocity of the Euclidean distance (A-C) were significantly decreased. When the two groups were directly compared, the 4-channel group showed significantly greater improvement in horizontal distance (A–B), Euclidean distance (A–D), time interval (A–B–C), and mean velocity the Euclidean distance (A–D). The results in this study suggest that the sequential 4-channel NMES might lead to the physiologic circular movement of the hyoid bone during swallowing, and therefore be an effective treatment for dysphagia.Trial registration: Clinicaltrials.gov, registration number: NCT03670498.

show abstract

Section: Introductionmentioning

confidence: 77%

Section: Introductionmentioning

confidence: 99%

Kinematic mechanism of the rehabilitative effect of 4-channel NMES: post-hoc analysis of a prospective randomized controlled study

Lim,

Lee,

Jang

et al. 2023

Sci Rep

Self Cite

View full text Add to dashboard Cite

show abstract

“…Primary outcomes included safety (Penetration-Aspiration Scale, PAS) 28 and performance outcomes (Functional Oral Intake Scale, FOIS) 29 of swallowing. Secondary outcomes included the severity of dysphagia (such as Functional Dysphagia Scale 30 and Videofluoroscopic Dysphagia Scale 31 ) and indicators of swallowing physiology (such as hyoid movement 32 and tongue pressure 33 ).…”

Section: Methodsmentioning

confidence: 99%

Efficacy and safety of oropharyngeal muscle strength training on poststroke oropharyngeal dysphagia: a systematic review and meta-analysis

Gao,

Xu,

Wang

et al. 2023

BMJ Open

View full text Add to dashboard Cite

ObjectivesTo investigate how oropharyngeal muscle strength training affected the safety and performance of swallowing in patients with poststroke oropharyngeal dysphagia.DesignSystematic review and meta-analysis.Data sourcesCochrane Central Register of Controlled of Trials, Web of Science, PubMed, Embase databases and ClinicalTrials.gov were systematically searched, for publications in English, from database inception to December 2022.Eligibility criteriaStudies comparing the effect of oropharyngeal muscle strength training with conventional dysphagia therapy in patients with poststroke. Penetration-Aspiration Scale (PAS) and Functional Oral Intake Scale (FOIS) were assessed as the main outcomes.Data extraction and synthesisTwo researchers independently screened the literature, extracted data and evaluated the quality of the included studies, with disagreements resolved by another researcher. The Cochrane risk-of-bias tool was used to assess the risk of bias. Review Manager V.5.3 was employed for the meta-analysis. Random effect models were used for meta-analysis.ResultsSeven studies with 259 participants were included in this meta-analysis. The results showed that oropharyngeal muscle strength training could reduce PAS score compared with conventional dysphagia therapy (mean difference=−0.98, 95% CI −1.34 to −0.62, p<0.0001, I2=28%). The results also showed that oropharyngeal muscle strength training could increase FOIS score (mean difference=1.04, 95% CI 0.55 to 1.54, p<0.0001, I2=0%) and the vertical displacement of the hyoid bone (mean difference=0.20, 95% CI 0.01 to 0.38, p=0.04, I2=0%) compared with conventional dysphagia therapy.ConclusionIn patients with poststroke oropharyngeal dysphagia, oropharyngeal muscle strength training can improve swallowing safety and performance.PROSPERO registration numberCRD42022302471.

show abstract

“…Secondary outcome measures include (1) severity of dysphagia assessed through Functional Dysphagia Scale, 25 Videofluoroscopic Dysphagia Scale, 26 Dysphagia Outcome and Severity Scale 27 and Dysphagia Rating Scale 28 ; (2) swallowing biomechanics with changes in maximal excursion of the hyoid, muscle strength of suprahyoid muscles and tongue pressure; (3) swallow-related quality of life assessed through Swallow Quality of Life Questionnaire. 29 …”

Section: Methods and Analysismentioning

confidence: 99%

Safety and performance of oropharyngeal muscle strength training in the treatment of post-stroke dysphagia during oral feeding: protocol for a systematic review and meta-analysis

Gao

Wang

et al. 2022

BMJ Open

View full text Add to dashboard Cite

IntroductionDysphagia is a common functional disorder after stroke. Most patients post-stroke are incapable of oral feeding, which often leads to complications such as malnutrition, aspiration pneumonia and dehydration that seriously affect the quality of life of patients. Oropharyngeal muscle strength training is a major method of swallowing training, and recent studies have focused on healthy adults, elderly persons, and patients with head and neck cancer or neurodegenerative diseases; but there have been few studies on such training in patients with post-stroke dysphagia. Our study aims to systematically review the safety and performance of oropharyngeal muscle strength training in the treatment of post-stroke dysphagia during oral feeding.Methods and analysisThe Cochrane Library, Web of Science, PubMed, Embase and ClinicalTrials.gov databases will be systematically searched, and all relevant articles in English from the establishment of the databases to January 2022 will be reviewed. The study will be conducted in accordance with the recommendations of the Cochrane Handbook for Systematic Reviews of Interventions and will be reported in accordance with Preferred Reporting Items for Systematic Reviews and Meta Analyses guidelines. The primary outcome measures include the Penetration–Aspiration Scale and the Functional Oral Intake Scale. Two authors will independently screen the articles, extract the data and assess the study quality. Any disagreements during this process will be resolved by discussion or by consultation with a third author. Next, quantitative or qualitative, subgroup and sensitivity analyses of the included literature data will be performed as appropriate.Ethics and disseminationEthical approval is not required for this systematic review as no primary data collection will be required. The results of the present study will be published in a peer-reviewed journal in the field of deglutition disorders.PROSPERO registration numberCRD42022302471.

show abstract

Clinical effectiveness of the sequential 4-channel NMES compared with that of the conventional 2-channel NMES for the treatment of dysphagia in a prospective double-blind randomized controlled study

Cited by 5 publications

References 32 publications

Kinematic mechanism of the rehabilitative effect of 4-channel NMES: post-hoc analysis of a prospective randomized controlled study

Kinematic mechanism of the rehabilitative effect of 4-channel NMES: post-hoc analysis of a prospective randomized controlled study

Efficacy and safety of oropharyngeal muscle strength training on poststroke oropharyngeal dysphagia: a systematic review and meta-analysis

Safety and performance of oropharyngeal muscle strength training in the treatment of post-stroke dysphagia during oral feeding: protocol for a systematic review and meta-analysis

Contact Info

Product

Resources

About