Clinical, educational, and epidemiological value of autopsy

Burton, Julian; Underwood, James

doi:10.1016/s0140-6736(07)60376-6

Cited by 357 publications

(301 citation statements)

References 85 publications

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“…The results from this study serve as a reminder of some of the possible consequences of a decreasing autopsy rate (28). Survival estimates for the majority of injury categories were unaffected by the addition of autopsy data.…”

Section: Discussionmentioning

confidence: 77%

The impact of clinically undiagnosed injuries on survival estimates

Gedeborg

Thiblin

Byberg

et al. 2009

Critical Care Medicine

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Section: Discussionmentioning

confidence: 77%

The impact of clinically undiagnosed injuries on survival estimates

Gedeborg

Thiblin

Byberg

et al. 2009

Critical Care Medicine

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“…As a means of keeping updated with anatomy over time, students on clinical rotations are encouraged to attend autopsies (Parker, 2002;Burton and Underwood, 2007). Unlike preserved and discolored cadavers, newly deceased patients are much more realistic, accompanied with medical histories and possess signs that govern diagnostic and prognostic implications.…”

Section: Autopsymentioning

confidence: 99%

The anatomy of anatomy: A review for its modernization

Sugand

Abrahams

Khurana

2010

Anatomical Sciences Ed

718

815

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Anatomy has historically been a cornerstone in medical education regardless of nation or specialty. Until recently, dissection and didactic lectures were its sole pedagogy. Teaching methodology has been revolutionized with more reliance on models, imaging, simulation, and the Internet to further consolidate and enhance the learning experience. Moreover, modern medical curricula are giving less importance to anatomy education and to the acknowledged value of dissection. Universities have even abandoned dissection completely in favor of user-friendly multimedia, alternative teaching approaches, and newly defined priorities in clinical practice. Anatomy curriculum is undergoing international reformation but the current framework lacks uniformity among institutions. Optimal learning content can be categorized into the following modalities: (1) dissection/prosection, (2) interactive multimedia, (3) procedural anatomy, (4) surface and clinical anatomy, and (5) imaging. The importance of multimodal teaching, with examples suggested in this article, has been widely recognized and assessed. Nevertheless, there are still ongoing limitations in anatomy teaching. Substantial problems consist of diminished allotted dissection time and the number of qualified anatomy instructors, which will eventually deteriorate the quality of education. Alternative resources and strategies are discussed in an attempt to tackle these genuine concerns. The challenges are to reinstate more effective teaching and learning tools while maintaining the beneficial values of orthodox dissection. The UK has a reputable medical education but its quality could be improved by observing international frameworks. The heavy penalty of not concentrating on sufficient anatomy education will inevitably lead to incompetent anatomists and healthcare professionals, leaving patients to face dire repercussions. Anat Sci Educ 3:83-93, 2010.

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“…The misdiagnosis on two separate histologic samples in this case highlights both the importance of autopsy in educating the medical community, and the challenges in making this diagnosis [16,17]. The diagnostic criteria for MFH is a continuous subject of debate amongst pathologists [13].…”

Section: Discussionmentioning

confidence: 90%

A Unique Case of Rapidly Progressive Diffuse Pulmonary Nodules

Weiler¹,

Puopolo²,

Newmarch³

et al. 2017

Pulm Crit Care Med

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The following case report describes a unique presentation of primary malignant fibrous histiocytoma (MFH) originating in the right ventricle. A 71-year-old male presented to the emergency department with tachycardia, dyspnea, tachypnea, and left leg pitting edema, seven weeks following a right total hip arthroplasty. Six weeks prior to presentation, the patient was diagnosed with pulmonary embolism and five pulmonary nodules based on computed tomography (CT) angiography. Laboratory studies at this time indicated anemia of chronic disease, consistent with results from six weeks earlier. Broncho-alveolar lavage (BAL) cytology suggested adenocarcinoma. CT angiography demonstrated a dramatic increase in the amount and extent of the pulmonary nodules previously noted in addition to an unresolved embolus of the right upper lobe. CT-guided biopsy was performed and confirmed a definitive diagnosis of non-small cell lung cancer. Two days after CT-guided biopsy, the patient developed acute hypotension and hypoxic respiratory failure rapidly progressing to asystole and subsequent death. Autopsy revealed a primary intra-cavitary malignant fibrous histiocytoma in the right ventricle, and multiple nodular tumours throughout the lung parenchyma with chest wall invasion. These findings allowed for a revision of the diagnosis and clinical-pathological picture. This case illustrates the limitations of radiological imaging in visualizing vascular structures, and the continued importance of autopsy in achieving a complete and correct pathological diagnosis. Moreover, this case draws light to the unclear diagnostic criteria for MFH and lack of effective treatment options. The longest documented survival of MFH is eight years, which was achieved with orthotopic cardiac transplantation.

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Clinical, educational, and epidemiological value of autopsy

Cited by 357 publications

References 85 publications

The impact of clinically undiagnosed injuries on survival estimates

The impact of clinically undiagnosed injuries on survival estimates

The anatomy of anatomy: A review for its modernization

A Unique Case of Rapidly Progressive Diffuse Pulmonary Nodules

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