Clinical Dynamics of Anemia in Pregnancy: A 16-week Cross-sectional Study of Pregnant Women Who Attended Antenatal Clinic of Federal Medical Center, Keffi, Nasarawa State, Nigeria

Inya, Azubuike Uma; Achara, Amaechi Peter; Ikwuka, Aloysius Obinna; Udeh, Francis Chigozie; Chi-kadibia, Ukoma; Onazi, Ochima

doi:10.12691/ajcmr-11-1-1

Cited by 3 publications

(1 citation statement)

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“…Among these major free radicals, superoxide anion, hydroxyl radical, and hydroperoxyl radical are of physiological significance. Non-radical of physiological significance is hydrogen peroxide [2,3,12,28,37,38,50,51]. Patients with Vitamin K deficiency are prone to different degrees of bleeding which can lead to anemia [27].…”

Section: Of 16mentioning

confidence: 99%

Optimization of Delirium Care in Adult Patients with Cancer: A Comprehensive and Integrative Review of Efficacy and Patient Outcomes

Ojiaku,

Duru,

Ikwuka

et al. 2024

WJCMR

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Delirium is a major complication most commonly observed in patients with advanced cancer. However, despite its prevalence, the early diagnosis, management, and prevention of this condition have not seen significant progress. Aim of this research is to provide insights into the prevalence of delirium, the optimization of interventions for managing delirium symptoms, their effectiveness and the impact of underlying factors on the reversibility of delirium in advanced cancer patients receiving palliative care. The review involved systematic searches of relevant databases including MEDLINE, CINAHL, ProQuest Nursing and Allied Health, and PsychInfo using refined search terms. Eight publications out of 614 studies originally searched were selected and critically reviewed. Their quality was assessed using Joanna Briggs Institute's Critical Appraisal Tool for Case Series. Data abstraction and content analysis were performed to synthesize the findings. Delirium is prevalent among advanced cancer patients in palliative care, with rates ranging from 10.3% to 24.1%. Pharmacotherapy and non-pharmacological interventions showed effectiveness in reducing delirium symptoms. Delirium was found to be reversible through palliative care interventions, antipsychotic medications, and exercise therapy. Effective delirium management is crucial in improving the quality of life of cancer patients. This review emphasizes the importance of subtype-specific treatments, standardized guidelines, and long-term follow-up studies. Implementing evidence-based individualized approaches to delirium management can optimize treatment efficacy and clinical outcomes in patients as well as improve the quality of care. Tailored interventions, standardized protocols, and further research are hereby recommended.

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Section: Of 16mentioning

confidence: 99%

Optimization of Delirium Care in Adult Patients with Cancer: A Comprehensive and Integrative Review of Efficacy and Patient Outcomes

Ojiaku,

Duru,

Ikwuka

et al. 2024

WJCMR

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Molecular Detection of Extended-Spectrum Beta-lactamase Producing Salmonella typhi Isolates in Patients Attending a Tertiary Care Hospital in North-Central Nigeria

2024

AJPAB

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Indiscriminate and irrational use of antibiotics has led to the emergence of antibiotic resistance of Salmonellatyphi (S. typhi) and the rapid spread of extended-spectrum beta-lactamase (ESBL) producing strains conferring resistance. This is in fact worrisome, is threatening antibiotic therapy and placing a substantial clinical and financial burden on the healthcare system, patients and their families. Aim of research was to detect molecularly extended-spectrum beta-lactamase producing S. typhi isolates in patients attending Bingham University Teaching Hospital (BhUTH), Jos, Plateau State, North-Central Nigeria. A total of 353stool samples were collected from patients attending BhUTH, and identified using standard microbiological techniques. Antibiotics susceptibility testing was carried out using disc diffusion method, and double disc synergy test (DDST) for phenotypic ESBL production. Polymerase Chain Reaction (PCR) and agarose gelelectrophoresis were done to detect the presence of ESBL genes. S. typhi prevalence was 37(10.4%). Antibiotics susceptibility profile showed highest resistance to Augmentin and Ampicillin (100%) and less resistance to Nitrofurantoin (0%) and Cefuroxime (24.3%). The S. typhi isolates had CRX-AUG-AMP-AMX-STR-CH and CRX-AUG-AMP-AMX-STR as the most frequent resistant phenotypes (10.8%) with multidrug-resistant (MDR) isolates (73%). ESBL producing isolates were 5(13.5%). PCR and agarose gel electrophoresis confirmed the presence of blaCTX-M 2(40.0%), blaSHV 3(60.0%) and blaTEM 5(100.0%) on 857, 615, and 972 base pairs respectively. S. typhi isolates showed higher susceptibility to Nitrofurantoin and Cefuroxime. Prompt monitoring of antibiotics usage, resistance to antibiotics and public health education are therefore necessary in order to reduce bacterial disease burden.

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Knowledge, Attitude and Factors Associated with Depression in Tuberculosis Patients Attending Directly Observed Treatment Short-course (DOTS) Centers in South-West Nigeria

2024

EJMHS

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Tuberculosis (TB) is of grave public health concern globally with a reported 1.3 million deaths approximately, caused by the infection. TB infection is closely associated with depression which at its worst stage can bring up suicidal thoughts and death. This study aimed to assess knowledge, attitude, and factors associated with depression in TB patients attending Directly Observed Treatment Short course (DOTS) centers in Lagos State, South-West Nigeria. A descriptive, cross-sectional approach was used to evaluate responses from 301 TB patients at 8 DOTS centers in Lagos State. Data from the participants (respondents) was collected using interviewer-administered questionnaires. Patient Health Questionnaire-9 (PHQ-9) was used to determine the depression status of the participants. Obtained data was analyzed using SPSS version 23.0, with the Chi-square test being used to check for the association of selected factors with the depression status of the participants. The mean age of the respondents was 35.1±11.7 years. A majority (71.8%) of the respondents were males, 69.1% were Christians, Yorubas were most (52.2%), 88.4% earned <N150,000 monthly, and only 1 participant had no formal education. Knowledge of depression among the participants was average (fair) and the attitude was positive among 41% of them. Factors significantly associated with depression were the presentation of symptoms, drug therapy duration, stigma from family and friends, denial of privileges, HIV status, privacy during treatment, and family support (p<0.05). Factors like the thought that tuberculosis makes one depressed, period of being diagnosed, stage of treatment, distance to the treatment center, attitude of the treatment center staff, and time spent on a treatment day were significantly not associated with depression (p>0.05). Depression can be fatal. Therefore, TB patients receiving treatment should be well-enlightened about this mental disorder.

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Clinical Dynamics of Anemia in Pregnancy: A 16-week Cross-sectional Study of Pregnant Women Who Attended Antenatal Clinic of Federal Medical Center, Keffi, Nasarawa State, Nigeria

Cited by 3 publications

References 0 publications

Optimization of Delirium Care in Adult Patients with Cancer: A Comprehensive and Integrative Review of Efficacy and Patient Outcomes

Optimization of Delirium Care in Adult Patients with Cancer: A Comprehensive and Integrative Review of Efficacy and Patient Outcomes

Molecular Detection of Extended-Spectrum Beta-lactamase Producing Salmonella typhi Isolates in Patients Attending a Tertiary Care Hospital in North-Central Nigeria

Knowledge, Attitude and Factors Associated with Depression in Tuberculosis Patients Attending Directly Observed Treatment Short-course (DOTS) Centers in South-West Nigeria

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