Clinical differences between early‐ and late‐onset psoriasis in <scp>T</scp>hai patients

Chularojanamontri, Leena; Kulthanan, Kanokvalai; Suthipinittharm, Puan; Jiamton, Sukhum; Wongpraparut, Chanisada; Silpa‐archa, Narumol; Tuchinda, Papapit; Sirikuddta, Wararat

doi:10.1111/ijd.12515

Cited by 24 publications

(42 citation statements)

References 19 publications

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“…A study done in Thai population Contrary to this study, stated that 65.2% had early onset psoriasis and 34.5 % had late onset psoriasis. 22 The age of onset among males was 20 and teenage among females as per another hospital-based study in Seoul, but no such observation could be made from this study.…”

Section: Discussioncontrasting

confidence: 53%

A Descriptive Study on the Clinical Manifestations and Severity of Psoriasis in Patients Presenting to Dermatology Opd of a Tertiary Health Care Center in Central Kerala

Jayakumar¹,

Seena²

2018

jemds

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BACKGROUND Psoriasis is heterogeneous in its history, manifestations, presenting age, sites affected and environmental triggers. It presents as small localized lesions to generalized exfoliation type. An understanding of the most common clinical manifestation and degre e of severity will help improve the standards of treatment and in turn improve the quality of life of psoriatic patients. Only very few studies have gone through this. The aim is to study the different clinical manifestations, aggravating factors, severity and most common presentations among the psoriasis patients presenting to the Dermatology OPD of Government Medical College, Kottayam. MATERIALS AND METHODS This is a descriptive study conducted over a period of two months in the Department of Dermatology and Venereology, Government Medical College. The study was conducted with a semi-structured interview schedule recording history, examination, PASI score and diagnosis. The data so obtained was entered in Microsoft Excel and analyzed using SPSS software. RESULTS 30.5% of the study sample had a history of aggravation of disease with seasonal variations (Summer) and 25.6% showed multifactorial aggravation. 17.1% had a family history of psoriasis. 87.8% had localized lesions. 92.7% presented with plaques. The most common type was chronic plaque (36.6%). As per PASI, 56% had mild, 22% each had moderate and severe psoriasis. CONCLUSION Chronic plaque psoriasis is the most common clinical type and most people present at the mild stage of the disease. Moderate and severe forms can be reduced by avoiding the aggravating factors. Planning appropriate treatment can significantly improve the quality of life of psoriasis patients.

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Section: Discussioncontrasting

confidence: 53%

A Descriptive Study on the Clinical Manifestations and Severity of Psoriasis in Patients Presenting to Dermatology Opd of a Tertiary Health Care Center in Central Kerala

Jayakumar¹,

Seena²

2018

jemds

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“…Although there are some studies2526 that family history is associated with early onset age, but it was difficult to find a study to explain a relationship between family history and disease severity. However, López-Estebaranz et al27 recently presented that the severity of psoriasis was not affected by the presence of a family history.…”

Section: Discussionmentioning

confidence: 99%

The Clinical Profile of Patients with Psoriasis in Korea: A Nationwide Cross-Sectional Study (EPI-PSODE)

et al. 2017

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BackgroundPsoriasis is an immune-mediated, chronic inflammatory disease affecting multiple aspects of patients' lives. Its epidemiology varies regionally; however, nationwide epidemiologic data on psoriasis depicting profile of Korean patients has not been available to date.ObjectiveTo understand nationwide epidemiologic characteristics and clinical features of adult patients with psoriasis visited university hospitals in Korea.MethodsThis multicenter, non-interventional, cross-sectional study recruited 1,278 adult patients with psoriasis across 25 centers in Korea in 2013. Various clinical data including PASI, BSA, DLQI, SF-36 and PASE were collected.ResultsA total of 1,260 patients completed the study (male:female=1.47:1). The mean age was 47.0 years with a distribution mostly in the 50s (24.9%). Early onset (<40 years) of psoriasis accounted for 53.9% of patients. The mean disease duration was 109.2 months; mean body mass index was 23.9 kg/m2; and 12.7% of patients had a family history of psoriasis. Plaque and guttate types of psoriasis accounted for 85.8% and 8.4%, respectively. Patients with PASI ≥10 accounted for 24.9%; patients with body surface area ≥10 were 45.9%. Patients with DLQI ≥6 accounted for 78.8%. Between PASI <10 and PASI ≥10 groups, significant difference was noted in age at diagnosis, disease duration, blood pressure, waist circumference of female, and treatment experiences with phototherapy, systemic agents, and biologics.ConclusionThis was the first nationwide epidemiologic study of patients with psoriasis in Korea and provides an overview of the epidemiologic characteristics and clinical profiles of this patient population.

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“…early onset). 7 While the predominance of early-onset psoriasis was confirmed in samples from dermatology departments, outpatient clinics and self-reported patient surveys, 11,[22][23][24][25][26] recent population-based estimates suggested that late-onset psoriasis was the more common form. [27][28][29] The high frequency of late-onset psoriasis among incident cases probably reflects the underlying population age distribution, with late-onset psoriasis more common as the general population becomes older.…”

Section: Interpretation Of the Findings And Comparison With Existing mentioning

confidence: 99%

Incidence and prevalence of psoriasis in Israel between 2011 and 2017

Schonmann

Ashcroft

Iskandar

et al. 2019

Acad Dermatol Venereol

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Background Psoriasis is a common chronic inflammatory skin disease associated with a heavy burden of morbidity, disability and cost. The occurrence of the disease in Israel has not been previously investigated. Objectives To provide standardized estimates of trends in psoriasis incidence, prevalence and mortality among patients in Israel between 2011 and 2017. Methods Using electronic health records from Clalit Health Services, the largest nationwide public health provider in Israel, we conducted a population‐based study investigating trends in the annual incidence and prevalence of psoriasis between the years 2011 and 2017. We report age‐ and sex‐adjusted rates, using the standard European population as a reference. Results We identified 71 094 incident psoriasis cases. The mean (SD) age of onset was 42.4 (21.0) years with a bimodal distribution, peaking in the early ‘30s and early ‘60s. Late‐onset psoriasis, occurring after 40 years of age, accounted for 51.1% of incident cases. The annual psoriasis incidence rate was constant throughout the study period (280/100 000 person‐years). Psoriasis prevalence rose from 2.5% in 2011 to 3.8% in 2017. Conclusions Psoriasis prevalence is increasing in Israel, although its incidence is stable. Clinicians and policymakers should plan to address the growing demands in the clinical, economic and societal burden of psoriasis.

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Clinical differences between early‐ and late‐onset psoriasis in Thai patients

Abstract: The present study supports the hypothesis that there are clinical differences between EOP and LOP in Asian populations.

Cited by 24 publications

References 19 publications

A Descriptive Study on the Clinical Manifestations and Severity of Psoriasis in Patients Presenting to Dermatology Opd of a Tertiary Health Care Center in Central Kerala

A Descriptive Study on the Clinical Manifestations and Severity of Psoriasis in Patients Presenting to Dermatology Opd of a Tertiary Health Care Center in Central Kerala

The Clinical Profile of Patients with Psoriasis in Korea: A Nationwide Cross-Sectional Study (EPI-PSODE)

Incidence and prevalence of psoriasis in Israel between 2011 and 2017

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