2016
DOI: 10.1007/s00384-016-2644-0
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Clinical diagnostic accuracy of acute colonic diverticulitis in patients admitted with acute abdominal pain, a receiver operating characteristic curve analysis

Abstract: PurposeThe study investigated the capability of clinical findings, temperature, C-reactive protein (CRP), and white blood cell (WBC) count to discern patients with acute colonic diverticulitis from all other patients admitted with acute abdominal pain.MethodsThe probability of acute diverticulitis was assessed by the examining doctor, using a scale from 0 (zero probability) to 10 (100 % probability). Receiver operating characteristic (ROC) curves were used to assess the clinical diagnostic accuracy of acute co… Show more

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Cited by 16 publications
(15 citation statements)
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“…Together with other clinical findings, laboratory tests may be helpful to guide the clinician in the diagnosis [64]. Several studies indicate that C-reactive protein levels are correlated to the severity of disease and recurrence rates; however, certain discrimination between the stages of the disease is not possible [65][66][67][68]. Existing studies investigating the correlation between clinical findings and staging at imaging are very heterogeneous and generally not of high quality [29].…”
Section: What Are the Risk Factors For Diverticulosis Diverticulitismentioning
confidence: 99%
“…Together with other clinical findings, laboratory tests may be helpful to guide the clinician in the diagnosis [64]. Several studies indicate that C-reactive protein levels are correlated to the severity of disease and recurrence rates; however, certain discrimination between the stages of the disease is not possible [65][66][67][68]. Existing studies investigating the correlation between clinical findings and staging at imaging are very heterogeneous and generally not of high quality [29].…”
Section: What Are the Risk Factors For Diverticulosis Diverticulitismentioning
confidence: 99%
“…Formulas TPR = TP /( TP + FN ) and FPR = FP /( FP + TN ) are used to calculate the corresponding TPR and FPR values of the confusion matrix to obtain a co-ordinate pair (dot pair). The dot pairs make up the receiver operating characteristic (ROC) curve [ 37 ]. The AUC is the total area under the ROC.…”
Section: Results and Analysismentioning
confidence: 99%
“…[52, 53] Modifying primary care management has potential to reduce hospital presentations, recurrence, antibiotic use (important with concerns about increasing antibiotic resistance)[18]. Easier access to diagnostic tools (including CT scan and quick point-of-care CRP testing) within primary care to exclude either complicated DDI or acute DDI as a diagnosis,[54] and developing and applying better prognostic rules[55] have potential in this regard. Results of recent studies in secondary care have led to guidelines increasingly avoiding antibiotics for uncomplicated DDI.…”
Section: Discussionmentioning
confidence: 99%