Clinical Diagnosis of Bladder Outlet Obstruction in Patients with Benign Prostatic Enlargement and Lower Urinary Tract Symptoms: Development and Urodynamic Validation of a Clinical Prostate Score for the Objective Diagnosis of Bladder Outlet Obstruction

Abstract

T h e J ourn al o f U r o lo g y Copyright © 1996 by A m e r ic a n U ro lo g ic a l A s s o c ia t io n , I n c . Vol. 155, 1649-1654, May 1996 Conclusions: Clinical prostate score shows a superior correlation with bladder outlet obstruc tion than isolated objective parameters or symptom scores. CLINICAL DIAGNOSIS OF BLADDER OUTLET OBSTRUCTION IN PATIENTS WITH BENIGN PROSTATIC ENLARGEMENT AND LOWER URINARY TRACT SYMPTOMS: DEVELOPMENT AND URODYNAMIC VALIDATION OF A CLINICAL PROSTATE SCORE FOR THE OBJECTIVE

Three-year prospective study of 3228 clinical BPH patients treated with alfuzosin in General Practice

“…During the course of the treatment: the discrepancy between the early onset of maximum symptom score reduction at three months (754%) and the delayed onset of maximum HRQL improvement at twelve months ( 45%) emphasizes the need to measure longterm outcomes according to the patient's perspectives. In the same way, symptom reduction and HRQL improvement were sustained up to 36 months (748% and 43%, respectively); interestingly the storage score was signi®-cantly more reduced than voiding score, and it had been shown that the former was perceived by the patients as the most bothersome 12 and correlated more with HRQL changes. 38 Physical/functional dimension improved more than social life status and mental dimensions, which contrasts with ®ndings of Fowler and coworkers 39 and of Doll and colleagues 40 in patients who underwent surgery (prostatectomy and transurethral resection of prostate, respectively).…”

“…11 Patient's preferences have been proven to be the major in¯uence in the therapeutic choice in BPH and may be different from those of urologists. As mentioned by Rosier and coworkers, 12 the urologist's priorities were based on the degree of obstruction (peak-¯ow, residual urine measurement, pressure-¯ow studies) while patients are mostly bothered by storage symptoms and especially urgency, nocturia and daytime frequency. 13 It is stated that the degree to which urinary dif®culties bother the BPH patient and affects his daily activities varies considerably among individual patients reporting the same symptoms.…”

“…A symptom score (Boyarsky modi®ed) and a 20-item BPH speci®c HRQL score including three questions of sexuality (Urolife TM BPH QoL 20) were selfadministered at baseline, 3,6,12,18,24,30, and 36 months.Results: Two thousand ®ve hundred and seventy-nine patients (79.9%) completed the study at the end of three years. Symptom score was signi®cantly reduced by 54% at 3 months and this reduction was maintained up to 36 months (748.4%); HRQL score was signi®cantly improved by 45.4% at 12 months and this improvement was maintained up to 36 months ( 43.4%).…”

“…A symptom score (Boyarsky modi®ed) and a 20-item BPH speci®c HRQL score including three questions of sexuality (Urolife TM BPH QoL 20) were selfadministered at baseline, 3,6,12,18,24,30, and 36 months.…”

Noninvasive assessment of prostatic obstruction in elderly men with lower urinary tract symptoms associated with benign prostatic hyperplasia

“…The clinical prostate score (CLIPS), introduced by Rosier et al, 1 was composed of scores for prostate volume, maximal urinary flow rate, postvoid residual urinary volume, and voided volume and had a superior correlation with urodynamically objective BOO than did isolated parameters. The BOO number (BOON) introduced by van Venrooij and Boon, 2 was calculated from the prostate volume, maximal urinary free flow rate, and relative postvoid residual urine volume, defined as the postvoid residual urine volume divided by the bladder volume at a strong desire to void (times 100%).…”