CASE HISTORYMrs. L is a 38-year-old Caucasian female with a past psychiatric history of major depressive disorder (MDD), posttraumatic stress disorder (PTSD), borderline personality disorder (BPD), and opioid use disorder (OUD), three prior psychiatric hospitalizations, and a past medical history of migraine, hypothyroidism, psychogenic nonepileptic seizures, and chronic nonhealing abdominal wounds following a multiyear series of abdominal surgeries and complications, who self-presented to a hospital's emergency department (ED) with approximately one month of acute-on-chronic depression and suicidal ideation with a plan to commit suicide by self-inflicted gunshot wound or overdosing on pills. On initial evaluation in the ED, Mrs. L stated that she has felt chronically depressed for years; however, the depression had worsened within the past month. Mrs. L initially did not identify any specific stressors or life changes that led to the acute decompensation, but she later revealed that acute stressors include her son turning 18 and leaving home as well as physical pain. From the ED, she was admitted to a locked inpatient psychiatry unit for further evaluation and treatment, and was ultimately discharged home after several weeks.
Past Psychiatric HistoryMrs. L has formal psychiatric diagnoses of MDD, PTSD, BPD, and OUD. She sees an outpatient psychiatrist, who is also her therapist, in her hometown on a weekly basis with a purported positive therapeutic relationship but poor compliance with appointments. She has had two suicide attempts. The first was at age 24 when she cut her wrists-but "not deep enough to kill me." The second was at age 26 when she swallowed pills but vomited them back up because she thought of her children. She denies any substance use.Her first psychiatric admission was following a disappointing surgery appointment, after which she expressed suicidal ideation and had a series of seizures. She presented to the ED accompanied by her mother, a teddy bear, and a fleece blanket. At that time, she was on olanzapine 5 mg twice a day, morphine sulfate 60 mg daily, clonazepam 2 mg three times a day as needed, and alprazolam 2 mg three times a day as needed. She appeared to have had a seizure and to have broken a rib, but an extensive work-up was unrevealing; the diagnosis was psychogenic nonepileptic seizures. She was prescribed levetiracetam and followed by a neurologist. Since then, she has had two hospitalizations at a free-standing psychiatric hospital, at which wound manipulations necessitated transfers to outside hospitals, as detailed below in past surgical history.Medications on her last admission were as follows: clonazepam 1 mg four times daily, levothyroxine 88 mcg daily, lisdexamfetamine 70 mg daily, mirtazapine 60 mg nightly, oxycodone 10 mg twice a day, pregabalin 150 mg twice a day, quetiapine 300 mg nightly, topiramate 75 mg twice a day, and trazodone 75 mg nightly. She was prescribed venlafaxine 75 mg daily but selfdiscontinued without consulting with her psychiatrist.Past medication tr...