Clinical data analysis in retrospective study through equality adjustment between groups

Kwak, Sang Gyu; Shin, Im Hee

doi:10.7465/jkdi.2015.26.6.1317

Cited by 2 publications

(1 citation statement)

References 6 publications

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“…When comparing the two groups, controlling for the effects of basic characteristic variables such as age and sex and examining differences in clinical variables between groups with secured equivalence can enhance clinical explanatory power and facilitate clinical interpretation. In other words, if the test and control groups are not homogeneous in terms of basic characteristic variables, the results may be underestimated or overestimated and selection bias may occur [ 12 ]. Of course, there are statistical corrections to solve this problem, but it is important to secure homogeneity between the two groups, except for the variables to be compared in the first place.…”

Section: Introductionmentioning

confidence: 99%

Age and sex differences in comorbidities in adult temporomandibular disorders: A cross-sectional study using Korea National Health and Nutrition Examination Survey (KNHANES)

Park,

Auh

2024

PLoS ONE

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Objectives To investigate the relationship between Temporomandibular disorder (TMD) and associated comorbidities in groups matched according to age and sex. Methods Using data from the cross-sectional fifth Korea National Health and Nutrition Examination Survey (KNHANES). Of the 25,534 eligible KNHANES, 17,762 adults aged ≥19 years who responded to survey questionnaire on TMD and comorbidities. Subjects were classified into eight groups according to age and sex. Logistic regression analyses were performed to evaluate the association between TMD and comorbidities according to age and sex. Results Of the enrolled participants, 2,107 (11.86%) complained of ≥1 TMD symptoms. In all groups, odds ratios (ORs) for prevalence of TMD were >1 in those with tinnitus. Rhinitis was closely associated with TMD in 6 groups. ORs for TMD with comorbidities according to age and sex were as follows: hypertension, men aged 50–64 years (OR 0.62; CI 0.41–0.94); ischemic heart disease, men aged 35–49 years (4.38; 1.54–12.47); osteoarthritis, women aged 50–64 years (1.38; 1.03–1.86); diabetes mellitus, men aged 35–49 years (0.21; 0.05–0.88); depression, men aged 50–64 years (1.68; 1.00–2.83), women aged 35–49 years (1.39; 1.05–1.85) and women aged 65–80 years (2.01; 1.46–2.77); migraine, men aged 50–64 years (1.60; 1.14–2.25), women aged d35-49 years (1.44; 1.14–1.81) and women aged 35–49 years (1.43; 1.07–1.90); cold hypersensitivity in the hands and feet, men aged 19–34 years (1.64; 1.05–2.58), men aged 35–49 years (1.68; 1.04–2.70), men aged 65–80 years (1.74; 1.09–2.75) and women aged 35–49 years (1.45; 1.15–1.84); olfaction disorder, men aged 50–64 years (2.49; 1.39–4.43); voice disorder, men aged 50–64 years (2.25; 1.28–3.96) and women aged 65–80 years (1.69; 1.09–2.63) Conclusions This study confirmed that the types and effects of comorbidities related to prevalence of TMD may differ according to the patient’s age and sex and this result will increase the predictability of the onset of TMD.

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Section: Introductionmentioning

confidence: 99%

Age and sex differences in comorbidities in adult temporomandibular disorders: A cross-sectional study using Korea National Health and Nutrition Examination Survey (KNHANES)

Park,

Auh

2024

PLoS ONE

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Retrospective Medical Record Analysis on Frequent Disease of Collaboration: A Pilot Study

공¹,

이²,

황³

2021

J Int Korean Med

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Objectives: This pilot study aimed to confirm the possibility of applying our design to the main study, a retrospective medical record analysis of the diseases which have most frequently been treated with collaborations of Korean and Western medicine, and to identify what corrections and statistical models are needed to conduct the main study.Methods: Data were collected from a case report form developed for patients who received treatment in the medical institutions. Appropriate statistical techniques, like Propensity Score (PS) and Generalized Estimation Equation (GEE) models, were used to compare the indicators of collaboration and non-collaboration groups for patients in comparable diseases.Results: Using PS matching for each M and S disease group, the indicators were compared by balancing the collaboration and non-collaboration group, and the GEE models compared indicators between groups in each disease over follow-up. Through this process we identified two limitations, insufficient samples and a large deviation of the follow-up period.Conclusion: This pilot study confirmed that the study design and case report form are applicable. The main study will be conducted by collecting sufficient samples and reflecting deviation of follow-up period.

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Clinical data analysis in retrospective study through equality adjustment between groups

Cited by 2 publications

References 6 publications

Age and sex differences in comorbidities in adult temporomandibular disorders: A cross-sectional study using Korea National Health and Nutrition Examination Survey (KNHANES)

Age and sex differences in comorbidities in adult temporomandibular disorders: A cross-sectional study using Korea National Health and Nutrition Examination Survey (KNHANES)

Retrospective Medical Record Analysis on Frequent Disease of Collaboration: A Pilot Study

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