Clinical cross-reactivity among foods of the Rosaceae family

Rodríguez, Julia; Crespo, Jesús F.; Lopez-Rubio, Arancha; Cruz-Bértolo, J. de la; Ferrando-Vivas, Paloma; Vives, R.; Daroca, Pilar

doi:10.1067/mai.2000.106927

Cited by 86 publications

(70 citation statements)

References 20 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…In central Europe, OAS prevails [21], whereas in southern Europe these foods frequently trigger more severe, even life-threatening reactions [22]. Our observed reaction pattern is more similar to the one observed in other Mediterranean countries although with a discrete increase in the prevalence of OAS [6,10,11,12,13, 17]. …”

Section: Discussionsupporting

confidence: 61%

“…Local reactions such as localized contact urticaria (CU) and oral allergy syndrome (OAS) are observed in >50% of patients [6,10,11,12,13]. Systemic reactions (generalized urticaria/angioedema or anaphylaxis) are frequently observed (18–44%), even in the absence of OAS [6,10,11,12,13]. …”

Section: Introductionmentioning

confidence: 99%

“…Sensitization to this protein, although very frequent in northern European peach-allergic patients, is less frequently responsible for peach allergy in the Mediterranean area [13, 17]. …”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Clinical, Anamnestic and Serological Features of Peach Allergy in Portugal

Rodrigues-Alves

Lopez

Pereira-Santos³

et al. 2008

Int Arch Allergy Immunol

View full text Add to dashboard Cite

Background: Peach is a common food allergen source throughout Europe. The aim of this study was to characterize peach allergy in a Portuguese patient population. Methods: Thirty peach-allergic patients confirmed by double-blind placebo-controlled food challenges and 29 controls were included. All subjects completed a standardized questionnaire regarding symptoms and epidemiologic characteristics, skin prick tests with inhalant allergens and foods as well as specific IgE antibodies to peach, recombinant peach allergens rPru p 1, rPru p 3, rPru p 4 and cross-reactive carbohydrate determinants. Results: Thirty-seven percent of patients reported only oral allergy syndrome, while 37% reported generalized urticaria and/or angioedema, 17% localized contact urticaria and 10% anaphylaxis with peach. Sensitization to other Rosaceae fruits and tree nuts was present in 90 and 77% of the patients, respectively. Respiratory allergy history was associated with less severe symptoms (oral allergy syndrome or contact urticaria; p < 0.01) and positive skin prick test to peach peel or plum with more severe symptoms (urticaria and/or angioedema or anaphylaxis; p < 0.05). Ninety-seven percent were sensitized to Pru p 3, 13% to Pru p 4, 3% to Pru p 1 and 10% to cross-reactive carbohydrate determinants. Pru p 3 specific IgE was associated with Artemisia vulgaris sensitization and tree nut allergy (p < 0.05) but not with clinical severity. Conclusions: Half the patients reported systemic reactions to peach. Peach allergy appeared predominantly mediated by Pru p 3 but some patients were sensitized to Pru p 4. Applying a 0.10 kU_A/l cutoff level, the diagnostic value of combining the 3 recombinant allergens was noteworthy, with 100% sensitivity and 90% specificity.

show abstract

Section: Discussionsupporting

confidence: 61%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical, Anamnestic and Serological Features of Peach Allergy in Portugal

Rodrigues-Alves

Lopez

Pereira-Santos³

et al. 2008

Int Arch Allergy Immunol

View full text Add to dashboard Cite

show abstract

“…Эти антитела практически отсутствуют у жителей регионов, где не произрастают ли-ственные деревья. Развитие у пациента клиниче-ских симптомов СОА при употреблении в пищу персиков представляет собой диагностически значимый маркер сенсибилизации к Pru p 1 и его гомологам и, соответственно, наличие фруктово-березового синдрома [12,34].…”

Section: таблица 1 основные аллергены Pr-10 группыunclassified

Diverse Peach Allergy: Sensitization to Molecular Components of Allergens From Prunus Persica

Mokronosova¹,

Коровкина²

2014

Med.Imm.Rus

View full text Add to dashboard Cite

“…Other fruits from the Rosaceae family including: peach, apricot, plum, almond, cherry (Prunoideae subfamily), apple, and pear (Pomoideae subfamily) have also been increasingly reported as causes of allergic reactions, particularly in adults with pollinosis (Cuesta-Herranz et al, 1998;Rodriguez et al, 2000). Patients allergic to such fruits frequently have positive skin tests or radioallergosorbent test.…”

Section: Fruit Allergymentioning

confidence: 99%