Clinical Courses and Pathological Findings in Two Gay Male Patients with Acquired Immunodeficiency Syndrome infected in Japan

Abstract

This is a report on the clinical courses and pathological findings in two gay male patients with acquired immunodeficiency syndrome (AIDS) infected in Japan. Case 1. A 39 year-old Japanese homosexual male was diagnosed as amebic dysentery complicated with liver abscess on admission. He was placed on Metronidazole with complete relief. Serological tests

Invasive amoebiasis: an emerging parasitic disease in patients infected with HIV in an area endemic for amoebic infection

“…Eleven other cases of HIV-infected patients with IA from whom detailed clinical history could be obtained have been described in the literature (Table 3) [10][11][12][13][14][15]. Combined with our 18 patients, the majority of the patients were homosexual or bisexual men and had AIDS although CD4+ lymphocyte counts were not known in most reported cases.…”

“…IA often co-existed with other enteric infections, with CMV colitis being the most common. Co-infection might also contribute to the clinical manifestations in these patients [10][11][12][13][14][15]. In the report by Fatkenheuer et al [15] two cases of concurrent amoebic colitis and CMV colitis were diagnosed and they were successfully treated only with metronidazole and ganciclovir [15].…”

“…Similarly, cases of IA are only rarely or never reported in HIV-infected patients, either from developed [10][11][12][13][14][15] or developing countries [16][17][18][19][20]. The reason remains unclear why IA is rare in HIV-infected patients despite their declining T-cell immunity, the major immunity against E. histolytica infection [2,21].…”