Patients with cancer had a higher rate of all bleeding episodes, but the analysis for major bleeding included too few patients to conclude that cancer predicted for major bleeding. A large inception cohort shrdy identified cancer or severe anemia as a risk factor for bleeding after the initiation of anticoagulant ttrerapy (12). However many patients were anticoagulated after cardiac surgery 607o) and most patients Q77o) underwent invasive procedures during ttre hospitalization. These results, therefore, may not be directly comparable to patients with cancer who are treated for acute thromboembolism.