Clinical Contrast Sensitivity Function in Patients with Infantile Nystagmus Syndrome Before and After Eye Muscle Surgery

Abstract

Purpose: To test the hypothesis that eye muscle surgery in patients with infantile nystagmus syndrome improves contrast sensitivity function.Methods: This is a prospective, interventional case series analysis of clinical data before and after eye muscle surgery in 113 patients who had no previous surgical treatment. Outcome measures included: 1) Routine demography and clinical characteristics, 2) Binocular best-corrected visual acuity in the null position and 3) Contrast sensitivity function. All patients data was collected for this study immediately pre-surgery and 2 to 6 months after surgery. Parametric and non-parametric statistical analysis of outcome measure data collected for this study were performed using standard software on grouped data using computerized software.

Visual Status and Visual Challenges of Persons with Albinism in A Metropolitan City of Niger Delta Region, Nigeria

“…The inherent disruption of melanin synthesis in albinism, results in abnormality in the development of the visual system leading to several visual deficits including delayed visual maturation, nystagmus, iris trans-illumination, strabismus, optic nerve hypo-plasia, abnormal fovea, abnormal decussation of the optic chiasm, impaired colour vision, reduced contrast sensitivity and stereoacuity [8][9][10].…”