Clinical Concepts of Dry Socket

Cardoso, Camila Lopes; Rodrigues, Moacyr Tadeu Vicente; Júnior, Osny Ferreira; Garlet, Gustavo; Carvalho, Paulo Sérgio Perri de

doi:10.1016/j.joms.2009.09.085

Cited by 112 publications

(142 citation statements)

References 77 publications

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“…Dry socket is the most common postoperative complication following a tooth extraction, that onsets 2 to 4 days after surgery [1][2][3][4] . It was described for the first time by Crawford 5 .…”

Section: Introductionmentioning

confidence: 99%

“…Several attempts to manage dry socket have been described 6,7 in the literature employing a variety of materials, irrigation solutions and procedures within the socket, however, the best treatment modality has not been set. Indeed, each institution adopts a different protocol, and in spite of many studies and publications 4 , further investigations are still required to establish the best way to treat this problem.…”

Section: Introductionmentioning

confidence: 99%

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Experimental dry socket: microscopic and molecular evaluation of two treatment modalities

et al. 2011

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PuRPOsE: To evaluate two treatment modalities of dry socket in rats and to discuss the first findings of the molecular analysis in this experimental model. METHOds: 84 rats underwent a tooth extraction were divided in 4 groups: I-uninfected socket (control), II-infected socket without any treatment, III-infected socket treated with irrigation of 2% sodium iodide and 3% hydrogen peroxide solution, IV-infected socket submitted to curettage, irrigation with physiological saline solution and fulfilled with metronidazole paste as base. The groups were subdivided in postoperative sacrifice periods: 6/15/28 days. A quantitative and a qualitative microscopic analysis was performed. Also, a quantitative analysis was performed using a RealTimePCR to evaluate the genes expression in the wound healing: Collagen Type I/COL-I, vascular endothelial growth factor/VEGF, osteocalcin/OCN, alkaline phosphatase/ALP, runt-related transcription factor 2/ RUNX2 and tumor necrosis factor alpha/TNF-α. REsuLTs: The group I showed higher bone formation, followed by groups IV, III, II respectively. The group II presented higher inflammatory infiltrate and the wound healing was delayed compared with other groups. It was obtained a significant positive correlation between bone neoformation and the expression of OCN and RUNX2, inflammatory infiltrate with TNF-α and a negative correlation between bone neoformation and TNF-α. CONCLusION: No significant difference was found between the treatments. Key words: Wound Healing. Dry Socket. Hydrogen Peroxide. Sodium Iodide. Metronidazole. Rats. REsuMO OBJETIVO: Avaliar duas modalidades de tratamento da alveolite em ratos e discutir os primeiros achados de uma análise molecular neste modelo experimental. MéTOdOs: 84 ratos foram submetidos a uma extração dentária e foram divididos em quatro grupos: I-alvéolo não infectado (controle), II-alvéolo infectado sem tratamento, III-alvéolo infectado tratado com irrigação de iodeto de sódio a 2% e solução de peróxido de hidrogênio a 3%, IV-alvéolo infectado submetido à curetagem, irrigação com solução salina fisiológica e preenchimento com pasta a base de metronidazol. Os grupos foram subdivididos em períodos de sacrifício pós-operatório: 6/15/28 dias. Uma análise quantitativa e qualitativa microscópica foi realizada. Além disso, uma análise quantitativa foi realizada utilizando RealTimePCR para avaliar a expressão de genes no reparo alveolar: o colágeno tipo I / COL-I, o fator de crescimento endotelial vascular / VEGF, osteocalcina / OCN, fosfatase alcalina / ALP, fator de transcrição runt relacionados 2 / RUNX2 e fator de necrose tumoral alfa / TNF-α. REsuLTAdOs: O grupo I mostrou maior formação óssea, seguido pelos grupos IV, III, II, respectivamente. O grupo II apresentou maior infiltrado inflamatório e a cicatrização foi atrasada em comparação com outros grupos. Foi obtida uma correlação positiva entre a neoformação óssea e a expressão de OCN e RUNX2, infiltrado inflamatório com TNF-α e uma correlação negativa entre a neoformação óssea e TNF-α. CONC...

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Experimental dry socket: microscopic and molecular evaluation of two treatment modalities

et al. 2011

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“…This can be happen because the pain is subjective which is means that one sample can feel a different pain from another sample. The pain that still exist on the seventh postoperative day can be related to the delay of healing process of extraction socket [8,9].…”

Section: Resultsmentioning

confidence: 99%

Depiction of Post-Odontectomy Pain Levels in Universitas Sumatera Utara Hospital Period of February-March 2017

Syaflida¹,

Sugianto²

2018

Proceedings of the International Dental Conference of Sumatera Utara 2017 (IDCSU 2017)

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Abstract-Odontectomy is one of the most common minor surgery performed in dentistry. Every patients will experience postoperative pain after odontectomy. Pain is subjective, each individual reports pain based on his/her own perception. The pain rating scale is used to measure the pain intensity of a patient. The aim of this study was to find out the depiction of pain levels after odontectomy in the Universitas Sumatera Utara Hospital. This study was a descriptive study which the sample of this study is all of the odontectomy patients from 6 th February until 6

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“…27 A localized fibrinolysis (resulting from conversion of plasminogen to plasmin, which dissolves fibrin crosslinks) occurring within the socket and subsequently leading to loss of the blood clot is believed to underlie the pathogenesis of alveolar osteitis. There is an increased incidence of dry socket being reported in patients with poor oral hygiene, higher pre and postoperative microbial counts, pericoronitis and periapical infection.…”

Section: Dry Socketmentioning

confidence: 99%

Microbial Flora in Oral Diseases

Patil

Rao

Sanketh

et al. 2013

The Journal of Contemporary Dental Practice

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The oral cavity being the hub of gamut of microbes, promotes the establishment of distinct microbial communities, such as on the mucosa and teeth. Metabolism of these organisms facilitates the attachment and growth of the subsequent colonisers. A delicate balance is maintained in the microbial ecosystem, with these organisms contributing to normal development and defences. However, any change or disruption in the microbial profile due to either intrinsic or extrinsic factors can result in an unfavorable shift toward pathogenic organisms triggering various diseases like dental caries or periodontitis. Furthermore, recent findings also state that these microorganisms may lead to systemic diseases like diabetes or atherosclerosis. This article is an attempt to give an overview of the altered flora in diseased states.

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Clinical Concepts of Dry Socket

Cited by 112 publications

References 77 publications

Experimental dry socket: microscopic and molecular evaluation of two treatment modalities

Experimental dry socket: microscopic and molecular evaluation of two treatment modalities

Depiction of Post-Odontectomy Pain Levels in Universitas Sumatera Utara Hospital Period of February-March 2017

Microbial Flora in Oral Diseases

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