Clinical characterization of acute renal failure in multiple organ dysfunction syndrome

Soejima, Akinori; Miyake, Nobuyuki; Matsuzawa, Naoki; Waku, Masayuki; Fukuoka, Kazuhito; Kamiya, Yasushi; Kitamoto, Kiyoshi; Nagasawa, Toshihiko

doi:10.1007/bf02479936

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2013

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Cited by 2 publications

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“…15 Our patient presented MODS and hypercytokinemia. Renal necropsy findings were compatible with that of AKI in MODS and they could be described as ''cytokine nephropathy''.…”

Section: Discussionmentioning

confidence: 67%

Cytokine nephropathy in a patient with fatal Epstein–Barr virus-associated hemophagocytic syndrome

2013

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Occasionally, patients with acute Epstein-Barr virus (EBV) infection develop hemophagocytic syndrome (HPS). Acute kidney injury (AKI) is considered a strong prognostic factor, but very few data are available about the biopsy-proven renal involvement of EBV-HPS. Here we describe a previously healthy 17-year-old girl with EBV-HPS. Combination therapy failed and renal necropsy was performed. The renal histology showed that intact glomeruli, remarkable interstitial edema and some cellular infiltration, and protein casts. These findings were compatible with cytokine nephropathy as recently advocated. We suggest that hypercytokinemia may play an important role in the pathophysiology in AKI of EBV-HPS.

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“…15 Our patient presented MODS and hypercytokinemia. Renal necropsy findings were compatible with that of AKI in MODS and they could be described as ''cytokine nephropathy''.…”

Section: Discussionmentioning

confidence: 67%

Cytokine nephropathy in a patient with fatal Epstein–Barr virus-associated hemophagocytic syndrome

2013

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Curbing Inflammation in Burn Patients

Farina

Rosique

2013

International Journal of Inflammation

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Patients who suffer from severe burns develop metabolic imbalances and systemic inflammatory response syndrome (SIRS) which can result in multiple organ failure and death. Research aimed at reducing the inflammatory process has yielded new insight into burn injury therapies. In this review, we discuss strategies used to curb inflammation in burn injuries and note that further studies with high quality evidence are necessary.

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Clinical characterization of acute renal failure in multiple organ dysfunction syndrome

Cited by 2 publications

References 10 publications

Cytokine nephropathy in a patient with fatal Epstein–Barr virus-associated hemophagocytic syndrome

Cytokine nephropathy in a patient with fatal Epstein–Barr virus-associated hemophagocytic syndrome

Curbing Inflammation in Burn Patients

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