Clinical characteristics of the course of atopic dermatitis during pregnancy

Abstract

Introduction. Atopic dermatitis (AD) is a chronic hereditary recurrent skin disease. Dermatosis is the most common pathology in pregnant women among skin and allergic diseases. According to some reports, exacerbations of dermatosis during gestation worsen the course of pregnancy, childbirth and the postpartum period.Purpose of the study. Тo study of the features of the course of AD in pregnant women.Materials and methods. An open, comparative, prospective study was conducted in which 55 pregnant women with a diagnosis of AD in the acute stage took part. The SCORAD index was used to assess the severity. Beck’s Depression and Anxiety Scales were used to identify violations of the psychoemotional status. To assess the impact of the disease on vital activity – the dermatological index of the quality of life. The pruritus-5 D scale was used to analyze pruritus.Results. Among pregnant women, AD, newly diagnosed during pregnancy, was recorded in 20 (36.4%) women, in 23 (41.8%) – an exacerbation occurred during pregnancy after prolonged remission, in 12 (21.8%) – recorded annual aggravation in the spring and autumn seasons. The role of the hereditary factor was registered in 28 patients (50.9%). Among the pregnant women with AD included in the study, only 5 (9.1%) needed inpatient treatment for exacerbation of the disease, 50 (90.9%) were observed on an outpatient basis. Severe degree was recorded in 7 pregnant patients (12.7%), moderate severity – in 32 (58.2%), mild degree – in 16 (29.1%).Conclusion. The results of our research can serve as a basis for new directions of research work in terms of studying the etiopathogenetic and clinical aspects of AD in pregnant women.