Clinical characteristics of respiratory syncytial virus infection‐associated acute otitis media

Tomochika, Kiyoko; Ichiyama, Takashi; Shimogori, Hiroaki; Sugahara, Kazuma; Yamashita, Hiroshi; Furukawa, Susumu

doi:10.1111/j.1442-200x.2008.02768.x

Cited by 4 publications

(3 citation statements)

References 18 publications

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“…However, adenovirus was negatively associated with S pneumoniae in Aboriginal children. In a study from Japan, 31% of hospitalized children with RSV had AOM 27 . The children with AOM more often seemed to have had β‐lactamase nonproducing ampicillin‐resistant H influenzae in nasopharyngeal culture compared with children without AOM, but the difference was not significant.…”

Section: Discussionmentioning

confidence: 93%

Panel 5: Microbiology and Immunology Panel

Murphy

Chonmaitree

Barenkamp

et al. 2013

Otolaryngol.--head neck surg.

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Objective The objective is to perform a comprehensive review of the literature from January 2007 through June 2011 on the virology, bacteriology, and immunology related to otitis media. Data Sources PubMed database of the National Library of Medicine. Review Methods Three subpanels with co-chairs comprising experts in the virology, bacteriology, and immunology of otitis media were formed. Each of the panels reviewed the literature in their respective fields and wrote draft reviews. The reviews were shared with all panel members, and a second draft was created. The entire panel met at the 10th International Symposium on Recent Advances in Otitis Media in June 2011 and discussed the review and refined the content further. A final draft was created, circulated, and approved by the panel. Conclusion Excellent progress has been made in the past 4 years in advancing an understanding of the microbiology and immunology of otitis media. Advances include laboratory-based basic studies, cell-based assays, work in animal models, and clinical studies. Implications for Practice The advances of the past 4 years formed the basis of a series of short-term and long-term research goals in an effort to guide the field. Accomplishing these goals will provide opportunities for the development of novel interventions, including new ways to better treat and prevent otitis media.

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Section: Discussionmentioning

confidence: 93%

Panel 5: Microbiology and Immunology Panel

Murphy

Chonmaitree

Barenkamp

et al. 2013

Otolaryngol.--head neck surg.

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“…The most studies on RSV-infections are related to pulmonary diseases. During RSV-infection, children up to two years of age have a high risk of concomitant acute AOM as a complication (10). In a systemic review, Eisenhut had point out to extrapulmonary manifestations of RSV-infections, especially in patients with severe clinical presentation (5).…”

Section: Discussionmentioning

confidence: 99%

Hepatitis during respiratory syncytial virus infection – a case report

2013

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Introduction:Respiratory syncytial virus (RSV) infection is the most common cause of hospitalization in infants and small children. The aim was to present a 13-months old boy diagnosed with acute airway infection, acute otitis media (AOM) and hepatitis during the RSV-infection.Material and methods:Serum catalytic activities of alkaline phosphatase (ALP), aspartate aminotranspherase (AST), alanine aminotranspherase (ALT), gamma glutamyl transpherase (GGT), lactate dehydrogenase (LD), and concentrations of bilirubin were monitored during hospitalization and at control examination.Results:The child had clinical signs and symptoms of respiratory failure, AOM, and laboratory findings of virus infection and liver disease. On admission, catalytic activities of enzymes were markedly increased, especially the activity of ALP (10333 U/L, i.e. 24-fold increase in comparison with the upper reference limit). The highest increased in AST (339 U/L, 4.5-fold), ALT (475 U/L, 10.3-fold) and LD (545 U/L, 1.5-fold) were registered on the 3rd day, and the highest increase in GGT (68 U/L, 3.1-fold) occurred on the 11th day. Seven weeks after discharge AST, ALT, GGT and LD decreased into reference range, and ALP remain mildly increased (478 U/L, 1.1 fold increase). RSV was confirmed in nasal lavage fluid.Conclusion:Laboratory results in patient with RSV infection needs to be interpreted in the light of both, respiratory and extrapulmonary manifestations of the infection, respectively.

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“…It is known that children with respiratory syncytial virus infection frequently have complications of acute otitis media [3].…”

Section: Introductionmentioning

confidence: 99%