Clinical characteristics of patients diagnosed with COVID-19 in Beijing

Jin, Aihua; Yan, Benyong; Hua, Wei; Feng, Dandan; Xu, Bin; Liang, Lianchun; Guo, Caiping

doi:10.1016/j.bsheal.2020.05.003

Cited by 30 publications

(38 citation statements)

References 6 publications

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“…A detailed overview of study characteristics is presented in the Supplementary data, Table S2 . Most studies (84 studies) reported data on COVID-19 patients from China [ 3 , 4 , 10 , 11 , 28–38 , 42–44 , 46–53 , 55 , 56 , 58–77 , 85 , 87 , 88 , 90 , 107–109 , 112 , 118–123 , 132–135 , 137–140 , 142 , 143 , 146–148 , 150–160 ], 27 studies were conducted in the USA [ 11 , 12 , 25 , 27 , 40 , 57 , 78 , 81 , 84 , 94 , 98–101 , 103 , 105 , 111 , 114 , 116 , 124 , 129–131 , 136 , 141 , 145 , 149 , 163 ], 23 studies reported data from Europe [ 26 , 39 , 45 , 54 , 80 , 82 , 83 , 86 , 89 , 91–93 , 95–97 , …”

Section: Resultsmentioning

confidence: 99%

“…Sample size was <300 patients in 117 studies and 7 studies (4 from China, 2 from the USA and 1 from South Korea) contained a sample size >1000 patients [ 10 , 12 , 34 , 73 , 105 , 113 , 131 , 159 ]. The majority of studies (85 studies) reported data on general hospitalized patients [ 3 , 4 , 10 , 12 , 28 , 30–38 , 40–42 , 44 , 46–50 , 52 , 53 , 55 , 56 , 58–63 , 65–67 , 69–75 , 77 , 78 , 80 , 84 , 85 , 87 , 88 , 90–92 , 97 , 99–103 , 105–107 , 109 , 110 , 112 , 113 , 118 , 119 , 121 , 123 , 128 , 129 , 131 , 132 , 134–136 , 138–140 , 143 , 147 , 148 , 153 , 155 , 157 , 159 ], 32 studies solely included ICU patients [ 27 , 39 , …”

Section: Resultsmentioning

confidence: 99%

“…Laboratory characteristics at hospital admission are reported in the Supplementary data, Table S3 . Thirteen studies reported eGFR [ 3 , 26 , 63 , 64 , 66 , 92 , 102 , 105 , 107 , 112 , 137 , 138 , 140 ]. Reported mean serum creatinine varied from 0.54 to 11.8 (haemodialysis population) mg/dL.…”

Section: Resultsmentioning

confidence: 99%

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Acute kidney injury and kidney replacement therapy in COVID-19: a systematic review and meta-analysis

Janse

Jong

et al. 2020

Clinical Kidney Journal

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Background Acute kidney injury (AKI) can affect hospitalized patients with coronavirus disease 2019 (COVID-19), with estimates ranging between 0.5% and 40%. We performed a systematic review and meta-analysis of studies reporting incidence, mortality and risk factors for AKI in hospitalized COVID-19 patients. Methods We systematically searched 11 electronic databases until 29 May 2020 for studies in English reporting original data on AKI and kidney replacement therapy (KRT) in hospitalized COVID-19 patients. Incidences of AKI and KRT and risk ratios for mortality associated with AKI were pooled using generalized linear mixed and random-effects models. Potential risk factors for AKI were assessed using meta-regression. Incidences were stratified by geographic location and disease severity. Results A total of 3042 articles were identified, of which 142 studies were included, with 49 048 hospitalized COVID-19 patients including 5152 AKI events. The risk of bias of included studies was generally low. The pooled incidence of AKI was 28.6% [95% confidence interval (CI) 19.8–39.5] among hospitalized COVID-19 patients from the USA and Europe (20 studies) and 5.5% (95% CI 4.1–7.4) among patients from China (62 studies), whereas the pooled incidence of KRT was 7.7% (95% CI 5.1–11.4; 18 studies) and 2.2% (95% CI 1.5–3.3; 52 studies), respectively. Among patients admitted to the intensive care unit, the incidence of KRT was 20.6% (95% CI 15.7–26.7; 38 studies). Meta-regression analyses showed that age, male sex, cardiovascular disease, diabetes mellitus, hypertension and chronic kidney disease were associated with the occurrence of AKI; in itself, AKI was associated with an increased risk of mortality, with a pooled risk ratio of 4.6 (95% CI 3.3–6.5). Conclusions AKI and KRT are common events in hospitalized COVID-19 patients, with estimates varying across geographic locations. Additional studies are needed to better understand the underlying mechanisms and optimal treatment of AKI in these patients.

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Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

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Acute kidney injury and kidney replacement therapy in COVID-19: a systematic review and meta-analysis

Janse

Jong

et al. 2020

Clinical Kidney Journal

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“…In addition, there was neither correlation between CRP and albumin (-0.3277) nor between ESR and albumin (-0.0504) ( Table 1). Studies have revealed no/slight increase of ESR and CRP 36,38,39 while other studies showed inconsiderable decrease of serum albumin in mildmoderate COVID-19 patients 38,40 . Most importantly no studies conducted on post recovery patients addressing those markers.…”

Section: Resultsmentioning

confidence: 96%

Hypoalbuminemia in Severe COVID-19 Post Recovery Patients

Ali

Tawfeeq

et al. 2020

Preprint

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Pandemic Coronavirus disease 2019 (COVID-19) is a contagious disease affecting more than 200 countries, territories and regions. Thousands of studies have dealt with all aspects of the disease but little is known about post recovery status of the patients. Here, we examined ESR, CRP and serum albumin biomarkers in severe and mild-moderate COVID-19 post recovery patients. In severe group patients, serum albumin had a strong negative correlation with both ESR and CRP (R2= -0.861), (R2= -0.711) respectively. Also, there was a positive correlation between ESR and CRP (R2=0.85) in the same group. However, there was no correlation among mild-moderate group patients in those biomarkers. In addition, no correlation recorded between severe and mild-moderate groups. This finding concludes the sustained elevation of ESR and CRP with decreased serum albumin level in severe COVID-19 post recovery patients.

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“…Idetartoznak általában a 65 év fölöttiek, különösen a társbetegségekben -szív-és érrendszeri, előrehaladott vese-, légzőszervi, daganatos, immunológiai betegségekben -is érintettek, valamint a transzplantáción átesettek. 1,2,3,4 Fokozott veszélyeztetettséget jelent a cukorbetegség is, a gyakori társbetegségek, a cardiovascularis rizikó, a betegek többnyire magasabb életkora és gyakori túlsúlya folytán kiemelten annak 2-es típusú formája (T2DM). 5,6 Előző közleményünkben áttekintettük a járvány és a diabetes kapcsolatával foglalkozó irodalmi adatokat.…”

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Koronavírus-fertőzés cukorbetegeken – A 2020. évi COVID-19-járvány első fázisának tapasztalatai az ÉKC Új Szent János Kórházban

Schandl¹,

Veress²,

Lengyel³

et al. 2020

Diabetologia Hungarica

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Clinical characteristics of patients diagnosed with COVID-19 in Beijing

Cited by 30 publications

References 6 publications

Acute kidney injury and kidney replacement therapy in COVID-19: a systematic review and meta-analysis

Acute kidney injury and kidney replacement therapy in COVID-19: a systematic review and meta-analysis

Hypoalbuminemia in Severe COVID-19 Post Recovery Patients

Koronavírus-fertőzés cukorbetegeken – A 2020. évi COVID-19-járvány első fázisának tapasztalatai az ÉKC Új Szent János Kórházban

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Clinical characteristics of patients diagnosed with COVID-19 in Beijing

Cited by 30 publications

References 6 publications

Acute kidney injury and kidney replacement therapy in COVID-19: a systematic review and meta-analysis

Acute kidney injury and kidney replacement therapy in COVID-19: a systematic review and meta-analysis

Hypoalbuminemia&nbsp;in Severe COVID-19&nbsp;Post&nbsp;Recovery&nbsp;Patients

Koronavírus-fertőzés cukorbetegeken – A 2020. évi COVID-19-járvány első fázisának tapasztalatai az ÉKC Új Szent János Kórházban

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Hypoalbuminemia in Severe COVID-19 Post Recovery Patients