“…20,21 Human Herpesvirus-6 HHV-6 reactivation in the posttransplant population may present with a classic limbic encephalitis, also sometimes called "posttransplant limbic encephalitis" (PALE), 22 or it may be associated with nonspecific cognitive abnormalities, delirium, 23 or myelitis. 24 PALE typically presents 2 to 6 weeks after transplantation and is often associated with amnesia, headaches, confusion, seizures, and subclinical epileptic abnormalities, 25,26 as well as either hyponatremia or, more rarely, hypernatremia. 27 Diagnosis is made via lumbar puncture with a positive HHV-6 PCR, and there is often an associated mild lymphocytic pleocytosis, although false-…”