Clinical characteristics of ectopic pancreas in digestive system

Abstract

Aim: PThis study aims to investigate the clinical features and therapeutic strategy of ectopic pancreas (EP) in the digestive system. Methods: We performed a retrospective analysis of 191 pathologically, from January 2012 to December 2017, verified cases of EP over the past five years from the first affiliated hospital of Zhengzhou University to standardize the therapeutic regimen, which could provide better guidance for the future patients. According to the treatment methods the patients were divided into three groups: conservative treatment (Group A), endoscopic treatment (Group B), and surgery operation (Group C). They were performed to summarize their clinical characteristics and followup study on therapeutic effects. Results: The patients did not show significant symptoms (or physical examination) in the clinical manifestations, which were obviously symptom (81.15%, P < 0.001). Most of patients conduct endoscopic examination (91.62%, P < 0.001) and the size of tumor in B and C groups was significantly larger than that in group A (P < 0.000). Each patient was followed up for six months, all of the patients in these three groups showed no significant postoperative differences of gastrointestinal symptoms (P = 0.134) or mental stress (P = 0.357). However, the number of patients with awareness of disease in group B and group C was significantly higher than that in group A (P = 0.001). Conclusions: In this study, patients with EP show no characteristic clinical manifestations and endoscopic examination has a good diagnostic effect. Endoscopic therapy should be the first choice of treatment except for a large mass that must be treated surgically.