Clinical characteristics of Chinese patients with duration of type 2 diabetes &gt;40 years

Song, Tingting; Luo, Yingying; Wang, Xuhui; Li, Jing; Han, Qian; Zhu, Hong; Zhao, Wei; Li, Weidong; Sun, Zilin; Yang, Xilin

doi:10.1111/1753-0407.12375

Cited by 6 publications

(2 citation statements)

References 38 publications

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“…In addition, this study also found that the good glycemic control prevalence was negatively related to the duration of disease. This is consistent with previous findings, which found that glycemic control worsened over the course of the disease in patients with T2D ( 41 , 42 ). Early glycemic control has been shown to reduce the risk of complications and death in T2D patients, particularly in patients with a longer course of disease; the earlier glycemic control is initiated, the lower the risk of death ( 42 ).…”

Section: Discussionsupporting

confidence: 93%

Glycemic control and its influencing factors in type 2 diabetes patients in Anhui, China

Xing

Wang²,

Fang³

et al. 2022

Front. Public Health

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ObjectiveTo investigate the status of glycemic control and analyze its influencing factors in patients with type 2 diabetes (T2D) in Anhui, China.Methods1,715 T2D patients aged 18–75 years old were selected from 4 counties or districts in Anhui Province in 2018, using a convenience sampling method. All patients have undergone a questionnaire survey, physical examination, and a glycosylated hemoglobin (HbA1c) test. According to the 2022 American Diabetes Association criteria, HbA1c was used to evaluate the glycemic control status of patients, and HbA1c < 7.0% was defined as good glycemic control. The influencing factors of glycemic control were analyzed by multivariate unconditional logistic regression.ResultsThe prevalence of good glycemic control among people with T2D in the Anhui Province was low (22.97%). On univariate analysis, gender, education level, occupation, region, smoking, drinking, waist circumference and disease duration (all P < 0.05) were significantly associated with glycemic control. The factors associated with pool glycemic control were female gender [OR = 0.67, 95%CI (0.52, 0.86), P = 0.001], higher level of education [OR = 0.47, 95%CI (0.27, 0.83), P = 0.001], living in rural areas [OR = 1.77, 95%CI (1.39, 2.26), P < 0.001], central obesity [OR = 1.58, 95%CI (1.19, 2.09), P = 0.001] and longer duration of disease [OR = 2.66, 95%CI (1.91, 3.69), P < 0.001].ConclusionsThe prevalence of good glycemic control in people with T2D in Anhui Province was relatively low, and gender, region, education level, central obesity and course of the disease were influencing factors. The publicity and education on the importance of glycemic control should be further strengthened in T2D patients, and targeted intervention measures should be carried out for risk groups.

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Section: Discussionsupporting

confidence: 93%

Glycemic control and its influencing factors in type 2 diabetes patients in Anhui, China

Xing

Wang²,

Fang³

et al. 2022

Front. Public Health

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“…Cys C has been shown to be superior to serum creatinine as a marker in assessment of renal function and improves estimates of glomerular filtration rate (GFR) compared to creatinine-based methods alone [12][13][14][15]. In addition, studies have suggested that Cys C could be an independent factor in the prediction of all-cause mortality, CVD and incident congestive heart failure in subjects with coronary heart disease (CHD) [16][17][18][19][20].…”

Section: Introductionmentioning

confidence: 99%

Association of circulating cystatin C levels with type 2 diabetes mellitus: a systematic review and meta-analysis

Duan¹,

Huang²,

Tang³

2020

aoms

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A b s t r a c tIntroduction: This study aimed to systemically summarize the present literature about circulating cystatin C (Cys C) levels in type 2 diabetes mellitus (T2DM) and provide a more precise evaluation of Cys C levels in T2DM. Material and methods: Relevant studies about Cys C concentrations in T2DM were searched in PubMed, EMBASE and the Cochrane Library database (up to Oct 31 2018). We computed the pooled standard mean difference (SMD) with its 95% confidence interval (CI) of Cys C levels through a random-effect model. The Q test and the I 2 statistic were used to assess and quantify between-study heterogeneity; publication bias was evaluated through a funnel plot and Egger's linear regression test. Results: After the literature search and screening process, 14 studies with 723 T2DM patients and 473 healthy controls were finally included in the meta-analysis. The results showed that T2DM patients had significantly higher Cys C levels compared to healthy controls (SMD = 1.39, 95% CI: 0.92-1.86, p < 0.001). Publication bias was not detected based on the symmetrical shape of the funnel plot and the results of Egger's test (p = 0.452). Subgroup analyses suggested that variables of human race, age, gender, study sample size and disease duration have a relationship with Cys C level in T2DM patients. Conclusions: Overall, our study suggests that patients with T2DM have an elevated circulating Cys C level compared to healthy controls, and it is associated with race, age, gender, study sample size and disease duration. Further investigations are still needed to explore the causal relationship of aberrant Cys C concentrations in T2DM.

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Association of the combination of sleep duration and sleep quality with quality of life in type 2 diabetes patients

Zeng

Yin

et al. 2018

Qual Life Res

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Clinical characteristics of Chinese patients with duration of type 2 diabetes >40 years

Abstract: The present study suggests that Chinese patients with long-term T2DM also had increased risks of hyperglycemia and non-fatal CHD. Further studies are needed to investigate whether survival of these patients was associated with non-increased risk of DN.

Cited by 6 publications

References 38 publications

Glycemic control and its influencing factors in type 2 diabetes patients in Anhui, China

Glycemic control and its influencing factors in type 2 diabetes patients in Anhui, China

Association of circulating cystatin C levels with type 2 diabetes mellitus: a systematic review and meta-analysis

Association of the combination of sleep duration and sleep quality with quality of life in type 2 diabetes patients

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