“…14,15 Therefore, AHRU is considered to be a new clinical entity. 6,10 The etiology of AHRU has yet to be determined, but it is suspected to be associated with a reduction of blood flow to the rectum, where there are no exacerbating factors, such as gastric acid, as there are in the stomach. Because in previous reports patients with AHRU have been frequently characterized as having severe underlying disorders, including cerebrovascular diseases (Table 7), stress has been suspected as a cause of AHRU.…”