Clinical Characteristics of 7 Renal Cell Carcinoma Patients Developing a Solitary Pancreatic Metastasis After Nephrectomy

Onishi, T; Ohishi, Yukihiko; Iizuka, Norio; Suzuki, Yasuyuki; Shirakawa, Hiroshi; Hatano, Takashi; Tomita, Masayuki

doi:10.5980/jpnjurol1989.86.1538

Cited by 11 publications

(9 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Renal cell carcinoma is more notorious for being problematic in this regard. In a review of 752 renal cell carcinomas over a span of 38 years, it was found that 0.9% developed solitary pancreatic metastasis [65]. In many instances, the interval after the diagnosis to the development of metastasis was several years, sometimes even decades [1,3,4,15,18,21,23,26,28,30,31,34,65,66,71,74,83,86,87,89,93,94,98].…”

Section: Discussionmentioning

confidence: 99%

Secondary tumors of the pancreas: an analysis of a surgical and autopsy database and review of the literature

et al. 2004

View full text Add to dashboard Cite

The vast majority of pancreatic carcinomas are primary, and, among these, more than 90% are of ductal origin. However, a variety of extrapancreatic tumors may involve the pancreas secondarily and may manifest different clinicopathological characteristics and outcomes. In this study, pathology material from 973 surgical specimens and 4955 adult autopsy cases was reviewed to identify the tumors metastatic to or secondarily involving the pancreas. Biliary and periampullary neoplasms and tumors confined to peripancreatic soft tissue were excluded. In the autopsy series, the pancreas was involved by tumor in 190 cases, and 81 of these were secondary tumors. These were predominantly of epithelial origin, most commonly from lung (34), followed by GI tract (20), kidney (4), breast (3), liver (2), ovary (1), and urinary bladder (1). In addition, there were six tumors of hematopoietic origin, two melanomas, two sarcomas, and two mesotheliomas. Among the 973 surgical specimens, 38 cases contained metastatic tumors to the pancreas. Of these, 11 were lymphomas, and the others were carcinomas of stomach (7), kidney (6), lung (2), liver, prostate, ovary, uterus (1 case of each), and a Merkel cell carcinoma. In addition, there were three malignant gastrointestinal stromal tumors and one retroperitoneal leiomyosarcoma. In conclusion, lung cancer is the most common source of metastasis to pancreas, followed by gastrointestinal carcinomas and lymphomas. These tumors are usually seen in patients with disseminated disease and are detected mainly in autopsies. Secondary tumors constitute about 4% of pancreatic specimens in the authors' surgical database. Approximately one-third of them are clinically mistaken as primary tumors of the pancreas. These are predominantly hematopoietic malignancies or carcinomas of renal or gastric origin. Secondary tumors should be entertained in both the clinical and pathological differential diagnosis of pancreatic neoplasia.

show abstract

Section: Discussionmentioning

confidence: 99%

Secondary tumors of the pancreas: an analysis of a surgical and autopsy database and review of the literature

et al. 2004

View full text Add to dashboard Cite

show abstract

“…Our experience was supported by these observations. Clinical and pathologic factors associated with a relative favorable prognosis of pancreatic metastasis are listed in Table 1 [10][11][12][13].…”

Section: Discussionmentioning

confidence: 99%

Metastasectomy for renal cell carcinoma as a strategy to obtain complete remission

et al. 2010

View full text Add to dashboard Cite

We report a case of 67-year-old Japanese woman with two types of metastasectomy for metachronous metastases of renal cell carcinoma (RCC). The initial nephrectomy for left RCC was performed in April 1977. The pathological diagnosis was clear cell carcinoma grade1-2, pT1b. In May 1996, computed tomography (CT) revealed a tumor in the upper pole of the remaining right kidney. The renal tumor was enucleated in June 1996. The histopathological diagnosis of the tumors was clear cell carcinoma. In December 1998, conventional B-mode ultrasound US detected solid tumors in the uncus, body, and tail of pancreas, and the patient underwent partial pancreatectomy, preserving the pancreatic head. Histologically, the tumor consisted of clear cell carcinoma. Eleven years following the second metastasectomy, patient was disease free without adjuvant therapy.

show abstract

“…Eine Aufstellung von Hirota aus dem Jahre 1996 zeigt detailliert 66 Fa Èlle von Pankreasmetastasen eines Nierenzellkarzinoms [15]. [26]. Onishi gibt ein Duchschnittsalter von 48 Jahren an.…”

unclassified

“…Onishi gibt ein Duchschnittsalter von 48 Jahren an. Einen Geschlechtsunterschied oder einen Seitenunterschied der prima Èren Nephrektomie findet er nicht [26]. Das Stadium des Prima Èrtumors ist in der Regel niedrig, d. h. Stadium I oder II bei solita Èrer Pankreasmetastasierung [26].…”

unclassified

“…Deshalb werden die seltenen sekunda Èren tumoro Èsen Prozesse im Pankreas pra Èoperativ ha Èufig als prima Ères Pankreaskarzinom fehldiagnostiziert [45]. Da diese Metastasen ha Èufig im Corpus pancreatis [26] lokalisiert sind und damit fru Èhe Symptome eher selten sind, erfolgt die Detektion dieses Pankreastumors gelegentlich als Zufallsbefund beim Follow-up im Rahmen der Tumornachsorge des Nierenzellkarzinoms [14]. Ob allerdings deshalb eine lebenslange oder langzeitige Nachsorge nach Operation eines Nierenzellkarzinom, wie gelegentlich in der Literatur gefordert wird, bei der seltenen Konstellation von singula Èren Spa Ètmetastasen sinnvoll ist, bleibt fraglich [9,13,28,39].…”

unclassified

See 1 more Smart Citation

Die singuläre Spätmetastase eines Nierenzellkarzinoms im Pankreas - Ein ungewöhnlicher Pankreastumor -

Marusch

Koch²,

Dietrich³

et al. 2001

Zentralbl Chir

View full text Add to dashboard Cite

We present the rare case of a solitary pancreatic metastasis of renal cell cancer being the only manifestation of tumordissemination. In 1993 the patient underwent a transperitoneal nephrectomy for removal of a clear cell renal cancer. In 1998 during follow up we detected a pancreatic tumor which was treated by pancreas resection, splenectomy and resection of the colon transversum. The histology revealed a metastasis of the previously resected renal cancer. The postoperative recovery was impaired by the development of an abcess in the former pancreatic region. During the first year of follow up we did not find any signs for local or distant tumor recurrence. Pancreas resection adapted to the location of the tumor is the treatment of choice for isolated solitary late metastases of renal cell cancer.

show abstract

Clinical Characteristics of 7 Renal Cell Carcinoma Patients Developing a Solitary Pancreatic Metastasis After Nephrectomy

Cited by 11 publications

References 0 publications

Secondary tumors of the pancreas: an analysis of a surgical and autopsy database and review of the literature

Secondary tumors of the pancreas: an analysis of a surgical and autopsy database and review of the literature

Metastasectomy for renal cell carcinoma as a strategy to obtain complete remission

Die singuläre Spätmetastase eines Nierenzellkarzinoms im Pankreas - Ein ungewöhnlicher Pankreastumor -

Contact Info

Product

Resources

About