Clinical characteristics in a cohort of patients with chronic inflammatory demyelinating polyneuropathy: a retrospective study

Abstract

Objective:The objective of the study is to evaluate the chronic inflammatory demyelinating polyneuropathy (CIDP) clinical spectrum in a cohort of Mexican patients who benefit from social security. Materials and methods: A retrospective study of CIDP patients from 2010 to 2021. We documented neurological deficits, electrophysiological and laboratory parameters, diagnostic characteristics, disease activity, and clinical outcomes. Results: 36 cases met the criteria of the EAN/PNS 2021, the mean age was 58.25 ± 10.10 years, 50% were women, and 69.4% used intravenous immunoglobulin (IVIG). Concerning functional status, 63.9% had an independent walk and 86.1% had mild weakness in manual skills. The analysis of functional status showed better results in the IVIG treatment group. Conclusions: Similar to previous literature reports, 50% of our patients had stable active disease. Considering the heterogeneity of the disease, more research about treatment initiation and long-term results is warranted.