Clinical characteristics, ballooning pattern, and long-term prognosis of transient left ventricular ballooning syndrome

Song, Bong Gun; Hahn, Joo‐Yong; Cho, Soo-Jin; Park, Young Hwan; Choi, Sang-Jin; Park, Ji Han; Choi, Seung–Hyuk; Choi, Jin-Ho; Park, Seung Woo; Lee, Sang Hoon; Gwon, Hyeon‐Cheol

doi:10.1016/j.hrtlng.2009.07.006

Cited by 57 publications

(31 citation statements)

References 27 publications

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“…Previously published reports described a striking female predominance of this syndrome [1,2]. Second, to our knowledge, this is the first report showing inverted TTC after bronchoscopy with BAL.…”

Section: Fig 2 End-systolic (A) and End-diastolic (B) Echocardiograsupporting

confidence: 50%

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Inverted Tako-Tsubo Cardiomyopathy Associated with Bronchoalveolar Lavage

Ok¹,

Song²,

Park³

et al. 2011

Heart, Lung and Circulation

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Section: Fig 2 End-systolic (A) and End-diastolic (B) Echocardiograsupporting

confidence: 50%

“…In TTC, stressful events or acute physical stress such as gastrointestinal bleeding, pancreatitis, non-cardiac medical procedures and surgery might trigger this syndrome [2,[4][5][6]. Although the cause of TTC is unknown, exag- .…”

Section: Fig 2 End-systolic (A) and End-diastolic (B) Echocardiogramentioning

confidence: 99%

Inverted Tako-Tsubo Cardiomyopathy Associated with Bronchoalveolar Lavage

Ok¹,

Song²,

Park³

et al. 2011

Heart, Lung and Circulation

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“…The criteria for inclusion were as follows: (1) transient akinesia/dyskinesia beyond a single major coronary artery vascular distribution; (2) absence of significant coronary artery disease on coronary angiograms (diameter stenosis <50% by visual estimation) or absence of angiographic evidence of acute plaque rupture; and (3) new electrocardiographic (ECG) changes (ST-segment changes, T-wave inversion, or Q wave). 10 Cardiogenic shock was defined as a systolic blood pressure <90 mm Hg for ≥30 minutes that was not responsive to fluid administration alone, accompanied by evidence of tissue hypoperfusion in the setting of clinically adequate or elevated LV filling pressures. 11 Pulmonary edema was defined as the presence of rales at pulmonary examination or a radiographic report of pulmonary alveolar/interstitial congestion at initial chest x-ray.…”

Section: Study Subjectsmentioning

confidence: 99%

The Impact of Stressor Patterns on Clinical Features in Patients With Tako‐tsubo Cardiomyopathy: Experiences of Two Tertiary Cardiovascular Centers

Song

Yang

Hwang

et al. 2012

Clinical Cardiology

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Background: Tako-tsubo cardiomyopathy (TTC) is typically triggered by an acute emotional or physical stress event. The aim of this study was to investigate the impact of stressor patterns on clinical features, laboratory parameters, and electrocardiographic and echocardiographic findings in patients with TTC. Hypothesis: Clinical features are different according to stressor patterns. Methods: Of 137 patients enrolled from the TTC registry database, 14 patients had emotional triggers (E group), 96 had physical triggers (P group), and 27 had no triggers (N group). Results: Most clinical presentations and in-hospital courses were similar among the groups. However, the E group had a higher prevalence of chest pain (P = 0.006) and palpitation (P = 0.006), whereas the P group had a higher prevalence of cardiogenic shock (P = 0.040), than other groups. The P group had a significantly higher heart rate (P = 0.001); higher high-sensitivity C-reactive protein (P = 0.006), creatine kinase MB fraction (P = 0.045), and N terminal-probrain natriuretic peptide (P = 0.036) levels; higher left ventricular end-diastolic pressure (P = 0.019) and left ventricular end-systolic diameter (P = 0.002); but lower left ventricular ejection fraction (P = 0.018). The E group had lesser prevalence of apical ballooning pattern (P = 0.038) than other groups. The P group required more frequent use of inotropics (P = 0.041) and diuretics (P = 0.047) and had significantly longer intensive care unit (P = 0.014) and in-hospital stays (P = 0.001). Conclusions:The clinical features of TTC are different according to preceding stressor patterns. The TTC group with preceding physical stressors was less likely to have preserved cardiovascular reserve and more likely to require hemodynamic support than other groups. The overall prognosis of TTC is excellent, regardless of triggering stressors.

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“…3). In-hospital cardiac mortality from TCM ranges from 0 to 2% (3,13) while all-cause mortality ranges from 0 to 9% (2,6,13,14). A diagnosis of TCM as a cause of cardiac arrest and shock can only be made if the patient survives the initial insult (15).…”

Section: Discussionmentioning

confidence: 99%

Estimation of Risk Factors for Cardiogenic Shock in Takotsubo Cardiomyopathy: A Retrospective Study

Vaidya

Madhira

2017

ICFJ

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Introduction: Presentation of Takotsubo cardiomyopathy(TCM) widely varies amongst the patients, ranging from asymptomatic patients to cardiogenic shock or even cardiac arrest. The underlying risk factors inherent to the patient that predispose to a catastrophic presentation have not been delineated well in the past.Objective: To distinguish risk factors and presenting characteristics of patients diagnosed with cardiogenic shock from TCM.Methods: Total 51 angiography-confirmed TCM patients admitted in Upstate Hospital from 2010 – 2014 were compared retrospectively, 13 presenting with cardiogenic shock.Results: While TCM was predominantly common in elderly females, four of the total six male TCM patients presented with shock (Odds ratio= 8.0, p=0.027). TSH was higher in cardiogenic shock group. Patients with shock had significantly higher incidence of ST elevations on EKG and higher peak troponins. Moreover, ST elevations were predominantly in the inferior, anteroseptal and lateral leads in the shock group as compared to only the septal leads in the control group. Echocardiography revealed lower LV ejection fraction, LV outflow tract obstruction and concomitant significant mitral regurgitation in shock patients. No correlation was found with age, BMI, coronary disease risk factors (diabetes, hypertension, smoking), coincident infection, electrolyte imbalance, QTc interval length.Conclusion: Risk factors and pathophysiology for cardiogenic shock in TCM were identified. TCM in males is rare, but male gender is a risk factor for shock.

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Clinical characteristics, ballooning pattern, and long-term prognosis of transient left ventricular ballooning syndrome

Cited by 57 publications

References 27 publications

Inverted Tako-Tsubo Cardiomyopathy Associated with Bronchoalveolar Lavage

Inverted Tako-Tsubo Cardiomyopathy Associated with Bronchoalveolar Lavage

The Impact of Stressor Patterns on Clinical Features in Patients With Tako‐tsubo Cardiomyopathy: Experiences of Two Tertiary Cardiovascular Centers

Estimation of Risk Factors for Cardiogenic Shock in Takotsubo Cardiomyopathy: A Retrospective Study

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