Clinical characteristics and prognostic factors of primary malignant cardiac tumors

Abstract

Primary malignant cardiac tumors (PMCTs) are rare but highly lethal, and up to 75% of them are sarcomas, followed by lymphoma and mesothelioma. [1] Due to the rarity of this disease, most studies to date were small series or single case report. Although a few of them investigated the clinical characteristics and survival of PMCT patients, the factors influencing overall survival have not been well elucidated. [2][3][4] The Surveillance, Epidemiology, and End Results (SEER) program covers about 28% of the US population, collecting data on patient demographics, primary tumor site, tumor morphology, stage at diagnosis, survival, and mortality, including rich data of cardiac tumors. [5] In the present study, we described the clinical characteristics, identified the variables affecting the prognosis, and constructed a nomogram for patients with PMCTs using the data from the SEER database.Jiaojiao Qiu and Yun Sun contribute equally to this work.

Racial and ethnic characteristics and cancer-specific survival in Primary Malignant Cardiac Tumors

“…Population-based registries have been previously used to determine predictors of poor prognosis in PMCTs which include advancing age, comorbidity index, angiosarcoma histology, metastatic disease, chemotherapy, and residual disease (R2) after resection however, the role of race has not been fully understood ( 10 ). A relative increase in the utilization of population-based databases to study sociodemographic features of PMCTs has been seen in recent years ( 11 , 12 ).…”