Clinical characteristics and prognostic factors in acute coronary syndrome patients complicated with cardiogenic shock in Japan: analysis from the Japanese Circulation Society Cardiovascular Shock Registry

Sakamoto, Kazuo; Matoba, Tetsuya; Mohri, Masahiro; Ueki, Yasushi; Tsujita, Yasuyuki; Yamasaki, Masao; Tanaka, Nobuhiro; Hokama, Yohei; Fukutomi, Motoki; Hashiba, Katsutaka; Fukuhara, Rei; Suwa, Satoru; Matsuura, Hirohide; Tachibana, Eizo; Yonemoto, Naohiro; Nagao, Ken

doi:10.1007/s00380-019-01354-9

Cited by 17 publications

(11 citation statements)

References 35 publications

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“…The inclusion of non-STEMI patients presented high OR for 30-day mortality in both Killip classification groups (Table 3), which is consistent with our prospective cohort study in a Japanese population in the JCS Shock Registry. 3,18 Female sex was associated with higher mortality, a difference that is unexplained by this study, but is in accordance with previous Japanese and international cohort studies. [19][20][21] In this study, cardiac arrest, observed in 5.3% of Killip class IV patients, was independently associated with lower mortality (adjusted OR 0.65, CI 0.54-0.77), which is unexplainable from this study.…”

Section: Study Limitationssupporting

confidence: 93%

Institutional Characteristics and Prognosis of Acute Myocardial Infarction With Cardiogenic Shock in Japan　― Analysis From the JROAD/JROAD-DPC Database ―

Matoba

Sakamoto

Nakai

et al. 2021

Circ J

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JCS-certified teaching hospitals, revealed that the 30-day mortality of acute coronary syndrome (ACS) with cardiogenic shock was as high as 34%, which remains a challenge in emergency cardiovascular medicine. 3,4 Because comprehensive management of cardiogenic shock state as well as early reperfusion therapy is vitally important for the treatment of AMI with cardiogenic shock (i.e., Killip class IV), functionally sufficient medical facilities T he in-hospital mortality rate of acute myocardial infarction (AMI) has been decreased to 4-5% owing to the spread of coronary care units and the generalization of emergency coronary reperfusion therapy. 1,2 However, a recent report from the Japanese Circulation Society (JCS) Cardiovascular Shock Registry (2012-2015), a prospective, observational, multicenter, cohort study that accumulated 979 cardiovascular shock patients among

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Section: Study Limitationssupporting

confidence: 93%

Institutional Characteristics and Prognosis of Acute Myocardial Infarction With Cardiogenic Shock in Japan　― Analysis From the JROAD/JROAD-DPC Database ―

Matoba

Sakamoto

Nakai

et al. 2021

Circ J

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“…Many observational studies have shown the importance of high-sensitivity troponin T (hs-TnT) and red cell distribution width as predictors of cardiogenic shock [31]. It has also been described that hs-Troponin T values measured immediately after surgery is an independent predictor of postoperative cardiogenic shock requiring mechanical circulatory support [32].…”

Section: Discussionmentioning

confidence: 99%

Myocardial infarction with cardiogenic shock---the experience of a primary PCI centre from North-East Romania

Anghel¹,

Sascau²,

Stătescu³

2021

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Objectives: To evaluate the severity of acute myocardial infarction (AMI) complicated with cardiogenic shock (CS), by comparison with inferior and right ventricular AMI, which is also considered a severe form of myocardial infarction. Methods: In an observational study, from 774 patients with STEMI hospitalized in our Cardiology Institute, over one year and a half, only 120 patients met the inclusion and exclusion criteria (60 patients with CS and 60 patients with right ventricular AMI). Data collected included age, sex, vital signs, oxygen saturation, respiratory rate, left ventricular ejection fraction, right ventricular dysfunction, complications during hospitalization and coronarography results. Results: Patients with CS had a more severe systolic dysfunction (median ejection fraction 22.72 ± 12.30% vs. 41.93 ± 10.50%, P < 0.0001). Single-vessel disease was the most common in both groups, left anterior descending artery being the culprit artery in most patients with cardiogenic shock, 25% of them having residual lesions with a severity >75%. Using a multivariate analysis, we observed that for patients with CS, delayed coronary angiography evaluation, as well as the presence of severe triple-vessel disease, were associated with a higher risk of death. In-hospital mortality (53.33% vs. 8.33%, P < 0.0001) and ventricular arrhythmia were significantly higher in patients with CS (48.3% vs. 11.3%, P < 0.0001). Conclusions: Our study suggests that patients with AMI and CS can be considered the most severe form of myocardial infarction and should, therefore, benefit of prompt and appropriate treatment, to improve the outcome.

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“…Algunos estudios encuentran por análisis multivariado que la edad avanzada, hipotensión, coma profundo, insuficiencia cardíaca y lesión de tronco de coronaria izquierda son factores independientes de mortalidad a 30 días (23) . En Chile encontraron como predictores de mortalidad intrahospitalaria y global a la fracción de eyección del ventrículo izquierdo < 30% y la presencia de 2 o más vasos enfermos (15)…”

Section: Discussionunclassified

Características actuales y factores de riesgo de mortalidad en Choque Cardiogénico por Infarto de Miocardio en un hospital Latinoamericano

Guzmán-Rodríguez¹,

Polo-Lecca²,

Aráoz-Tarco³

et al. 2020

APCyCCV

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Objetivo. Conocer las características clínicas y determinar los factores relacionados a mayor mortalidad en pacientes con choque cardiogénico (CC) por infarto de miocardio en un hospital de referencia peruano. Materiales y métodos. Cohorte única prospectiva donde se evaluó la presentación, tratamiento y complicaciones de pacientes con CC por infarto de miocardio atendidos entre marzo 2019 a agosto 2020 en el Instituto Nacional Cardiovascular - INCOR. Se evaluaron los factores relacionados con mayor mortalidad hospitalaria y en el seguimiento, además del uso del score IABP shock II en la población de estudio. Resultados. Cuarenta pacientes fueron incluidos, el 75% con CC por disfunción ventricular izquierda, la mayoría varones con edad de 75 (69-82) años. Un 50% de casos presentaron CC luego del ingreso a emergencia. Los pacientes estratificados mediante el score IABP shock II como bajo, intermedio y alto riesgo, tuvieron una mortalidad intrahospitalaria de 37,5; 71;4 y 91,6% respectivamente. La mortalidad intrahospitalaria fue 70%, mayor en mujeres, mayores de 75 años y en los que desarrollaron el CC durante la hospitalización. En el análisis univariado, el lactato sérico > 4 mmol/L al ingreso se relacionó con mayor mortalidad (HR:2,8; IC:1,6-3,6, p=0,009). La sobrevida hasta el término del estudio fue de 12,8%. Conclusiones. EL CC por infarto de miocardio representa una entidad clínica de elevada mortalidad a pesar de la revascularización y el tratamiento disponible en nuestra realidad. El mayor predictor de mortalidad fue el valor de lactato sérico mayor a 4 mmol/L al ingreso. El score IABP shock II demostró ser un buen parámetro para estratificar el riesgo de muerte en nuestra población.

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Clinical characteristics and prognostic factors in acute coronary syndrome patients complicated with cardiogenic shock in Japan: analysis from the Japanese Circulation Society Cardiovascular Shock Registry

Cited by 17 publications

References 35 publications

Institutional Characteristics and Prognosis of Acute Myocardial Infarction With Cardiogenic Shock in Japan　― Analysis From the JROAD/JROAD-DPC Database ―

Institutional Characteristics and Prognosis of Acute Myocardial Infarction With Cardiogenic Shock in Japan　― Analysis From the JROAD/JROAD-DPC Database ―

Myocardial infarction with cardiogenic shock---the experience of a primary PCI centre from North-East Romania

Características actuales y factores de riesgo de mortalidad en Choque Cardiogénico por Infarto de Miocardio en un hospital Latinoamericano

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Clinical characteristics and prognostic factors in acute coronary syndrome patients complicated with cardiogenic shock in Japan: analysis from the Japanese Circulation Society Cardiovascular Shock Registry

Cited by 17 publications

References 35 publications

Institutional Characteristics and Prognosis of Acute Myocardial Infarction With Cardiogenic Shock in Japan ― Analysis From the JROAD/JROAD-DPC Database ―

Institutional Characteristics and Prognosis of Acute Myocardial Infarction With Cardiogenic Shock in Japan ― Analysis From the JROAD/JROAD-DPC Database ―

Myocardial infarction with cardiogenic shock---the experience of a primary PCI centre from North-East Romania

Características actuales y factores de riesgo de mortalidad en Choque Cardiogénico por Infarto de Miocardio en un hospital Latinoamericano

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Product

Resources

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Institutional Characteristics and Prognosis of Acute Myocardial Infarction With Cardiogenic Shock in Japan　― Analysis From the JROAD/JROAD-DPC Database ―

Institutional Characteristics and Prognosis of Acute Myocardial Infarction With Cardiogenic Shock in Japan　― Analysis From the JROAD/JROAD-DPC Database ―