Clinical characteristics and outcomes of patients with right congenital diaphragmatic hernia: A population-based study

Beaumier, Catherine K.; Beres, Alana L.; Puligandla, Pramod S.; Skarsgard, Erik D.

doi:10.1016/j.jpedsurg.2015.02.027

Cited by 28 publications

(24 citation statements)

References 25 publications

(22 reference statements)

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“…Subsequently, a more detailed expert evaluation should be performed to determine the location of the defect, the observed/expected lung-to-head ratio (O/E LHR) and the position of the liver (intra-abdominal or intrathoracic), in addition to ruling out additional congenital anomalies or syndromes [4,5]. Associated congenital anomalies, such as chromosomal or genitourinary anomalies, are present in about 25% [6] and cardiac anomalies in about 20% of cases [7]. Comprehensive assessment will also include invasive sampling for high-resolution genetic testing.…”

Section: Resultsmentioning

confidence: 99%

Standardized Postnatal Management of Infants with Congenital Diaphragmatic Hernia in Europe: The CDH EURO Consortium Consensus - 2015 Update

et al. 2016

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In 2010, the congenital diaphragmatic hernia (CDH) EURO Consortium published a standardized neonatal treatment protocol. Five years later, the number of participating centers has been raised from 13 to 22. In this article the relevant literature is updated, and consensus has been reached between the members of the CDH EURO Consortium. Key updated recommendations are: (1) planned delivery after a gestational age of 39 weeks in a high-volume tertiary center; (2) neuromuscular blocking agents to be avoided during initial treatment in the delivery room; (3) adapt treatment to reach a preductal saturation of between 80 and 95% and postductal saturation >70%; (4) target PaCO₂ to be between 50 and 70 mm Hg; (5) conventional mechanical ventilation to be the optimal initial ventilation strategy, and (6) intravenous sildenafil to be considered in CDH patients with severe pulmonary hypertension. This article represents the current opinion of all consortium members in Europe for the optimal neonatal treatment of CDH.

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Section: Resultsmentioning

confidence: 99%

Standardized Postnatal Management of Infants with Congenital Diaphragmatic Hernia in Europe: The CDH EURO Consortium Consensus - 2015 Update

et al. 2016

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“…The controversy over whether or not right-sided CDH is associated with inferior outcomes was addressed by the largest comparative study to date by Beaumier et al, which found no difference in survival, ventilatory outcomes, or length of stay, although right-sided defects were more likely to require patch repair and experience hernia recurrence. 45 Long-term follow-up of patients with CDH at the two largest CAPSNet sites showed high rates of growth impairment, hearing loss, and neurodevelopmental disability at 24 and 36 months of age, respectively. 46 The authors also conducted a survey regarding long-term follow-up practices at the 16 CAPSNet centers, finding that follow-up protocols were highly variable between sites, suggesting an opportunity to standardize follow-up care for CDH in Canada.…”

Section: Congenital Diaphragmatic Herniamentioning

confidence: 93%

The Canadian Pediatric Surgery Network (CAPSNet): Lessons Learned from a National Registry Devoted to the Study of Congenital Diaphragmatic Hernia and Gastroschisis

2015

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The Canadian Pediatric Surgery Network (CAPSNet) was created in 2005 by a geographically representative, multidisciplinary group of clinicians and researchers with the intent of establishing a national research registry for gastroschisis (GS) and congenital diaphragmatic hernia (CDH). Since then, CAPSNet has used this registry and its 16-center network to make contributions to the knowledge base informing best practices for GS and CDH care. More recently, CAPSNet has expanded its focus to include quality assurance and improvement at each of its sites, by issuing a benchmarked outcomes "report card" with its annual report. Finally, a major objective of CAPSNet has been to establish and adopt standardized, evidence-based practice guidelines for GS and CDH across all Canadian perinatal centers.

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“…The prenatal diagnosis of RCDH remains much more difficult than that of LCDH [ 1 ]. The ultrasonographic findings of LCDH are intrathoracic cystic lesions with a mediastinal shift to the right side and the absence of a fluid-filled stomach in the normal position.…”

Section: Discussionmentioning

confidence: 99%

“…Congenital diaphragmatic hernia (CDH) occurs at an incidence of 4 per 10,000 live births [ 1 ]. Right congenital diaphragmatic hernia (RCDH) occurs less frequently than left congenital diaphragmatic hernia (LCDH), accounting for 10% to 15% of all cases of CDH [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Impaction of an intrathoracic kidney acted as a shield against herniation of the abdominal viscera in a case of right congenital diaphragmatic hernia

et al. 2016

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We describe a case of an intrathoracic kidney combined with right congenital diaphragmatic hernia (CDH) that was diagnosed at 32 weeks of gestation. Although it has been well established that a right CDH shows a poorer outcome than a left CDH, our present case showed a good outcome because there was no herniation of other abdominal viscera, except for the right kidney. Our findings in this case indicate that impaction of the intrathoracic kidney may act as a 'shield' against further herniation of other abdominal viscera into the thoracic cavity.

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Clinical characteristics and outcomes of patients with right congenital diaphragmatic hernia: A population-based study

Cited by 28 publications

References 25 publications

Standardized Postnatal Management of Infants with Congenital Diaphragmatic Hernia in Europe: The CDH EURO Consortium Consensus - 2015 Update

Standardized Postnatal Management of Infants with Congenital Diaphragmatic Hernia in Europe: The CDH EURO Consortium Consensus - 2015 Update

The Canadian Pediatric Surgery Network (CAPSNet): Lessons Learned from a National Registry Devoted to the Study of Congenital Diaphragmatic Hernia and Gastroschisis

Impaction of an intrathoracic kidney acted as a shield against herniation of the abdominal viscera in a case of right congenital diaphragmatic hernia

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