Clinical Characteristics and Outcomes of Obstetric Patients Requiring ICU Admission

Vásquez, Daniela N.; Bakker, Jan; Canales, Héctor Saúl; Reina, Rosa; Saenz, María G; Neves, Andrea V. Das; Toro, Maria America; Loudet, Cecilia

doi:10.1378/chest.06-2388

Cited by 186 publications

(176 citation statements)

References 27 publications

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“…Scores based on criteria of organ/system dysfunction or failure, such as SOFA scores, have greater discriminatory power in cases of SMM [6,7,9,14,21]. Consequently, women who survive SMM after presenting with high SOFA scores may be classified as maternal near miss, as the high SOFA scores represent severe organ/system dysfunction or failure [1,[11][12][13][14][15] during their hospitalization.…”

Section: Discussionmentioning

confidence: 99%

“…It employs parameters from six organ systems-respiratory, cardiovascular, central nervous systems, renal, coagulation, and liver which are weighted (each 1-4) to give a final score [6-24 (maximum)]. The SOFA score has since then been validated to describe organ dysfunction in diverse patients with obstetric complications unrelated to sepsis [9][10][11] and has been validated to quantify the severity and extent of organ dysfunction and to predict prognosis for severely ill patients [12][13][14][15]. As the organ system functioning worsens, the score increases.…”

Section: Introductionmentioning

confidence: 99%

“…Studies that have evaluated SMM in intensive care units (ICU) have reported that the degree of organ dysfunction, the number of failing organs, and the duration of the condition are directly related to higher maternal mortality [12][13][14][15]. Prior studies have revealed high maternal morbidity and mortality related to severe obstetric complications in our setting [16,17].…”

Section: Introductionmentioning

confidence: 99%

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The Utility of the Sequential Organ Failure Assessment Score in Predicting Mortality in Critically Ill Obstetric Patients Admitted to a High Dependency Unit in Uganda

Kaye¹

2017

IPCB

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Background: Most maternal deaths result from severe maternal morbidity (SMM with subsequent organ/system dysfunction and organ failure. The objective was to assess the performance of Sequential Organ Failure Assessment (SOFA) score in cases of SMM admitted to the high dependency obstetric unit.Methods: Organ/system dysfunction and failure were assessed according to the maximum score for the six components (respiratory, neurological, renal, hepatic, cardiovascular and coagulation system). The total maximum SOFA score was estimated using the worst result each component on a single day. The distribution of SOFA scores was assessed for normality by using the Shapiro Wilk Test, [p=003]. The mean maximum SOFA scores for each organ/system were computed according to according to outcome (survival or death), using the Mann-Whitney test. The sensitivity, specificity, and the area under the curve (AUC) for each organ/system were evaluated. A Receiver Operator Characteristic (ROC) curve was fitted using maximum likelihood estimates for the total maximum SOFA score, in order to assess the sensitivity, specificity and discriminatory abilities of the maximum SOFA scores. Results:Of the 425 patients with SMM, 345 (81.2%, 95%CI 71.8-82.4) survived while 80 (18.8%, 95% CI: 12.9, 22.6) did not survive. All the non-survivors and 64 (18.5%) of the survivors presented with multiple organ/system dysfunction. Nonsurvivors were more likely to present with more severe and with multiple organ/ system dysfunction. The maximum total SOFA score had good discrimination in the respiratory, cardiovascular and neurological systems, but poor discrimination in the renal, hepatic and coagulatory systems. The total maximum SOFA score displayed an area under the curve (AUC) of 0.83 (95% CI: 0.56, 1.00), with a cutoff value of at least 8.0 sensitivity of 86.7%, and specificity of 90.0%. Conclusion:The total maximum SOFA score showed good predictive and discriminative abilities for maternal mortality in women with severe maternal morbidity.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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The Utility of the Sequential Organ Failure Assessment Score in Predicting Mortality in Critically Ill Obstetric Patients Admitted to a High Dependency Unit in Uganda

Kaye¹

2017

IPCB

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“…En esta serie, preeclampsia severa (PES) fue la primera causa de ingreso (47,2%), similar a otros centros: 44,5% y 36,6% 14,15 .…”

Section: Causas De Ingreso a Uciunclassified

“…Este resultado se compara favorablemente con dos series de Sud-América 15,29 , que comunican una mortalidad materna de 11% y 33,8% respectivamente, pero que incluyen casos con deficiente cuidado prenatal y sepsis por aborto.…”

Section: Parto E Ingreso a Uciunclassified

Morbilidad materna grave e ingreso a cuidado intensivo: Hospital Clínico Universidad de Chile (2006-2010)

Sepúlveda‐Martínez

et al. 2013

Rev. méd. Chile

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Epidemiology of Critical Illness in Pregnancy

Ananth

Smulian

2018

Critical Care Obstetrics

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Clinical Characteristics and Outcomes of Obstetric Patients Requiring ICU Admission

Cited by 186 publications

References 27 publications

The Utility of the Sequential Organ Failure Assessment Score in Predicting Mortality in Critically Ill Obstetric Patients Admitted to a High Dependency Unit in Uganda

The Utility of the Sequential Organ Failure Assessment Score in Predicting Mortality in Critically Ill Obstetric Patients Admitted to a High Dependency Unit in Uganda

Morbilidad materna grave e ingreso a cuidado intensivo: Hospital Clínico Universidad de Chile (2006-2010)

Epidemiology of Critical Illness in Pregnancy

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