Clinical characteristics and outcomes of in-hospital cardiac arrest among patients with and without COVID-19

Mortality after in-hospital cardiac arrest in patients with COVID-19: A systematic review and meta-analysis

“…After the exclusion of duplicates and not relevant records, ten articles were included, evaluating a total of 1179 COVID-19 patients after IHCA and attempted CPR. 5 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 The process of inclusion and exclusion, detailed in a the PRISMA flow diagram, is presented as Fig. S1 in Supplementary material 2.…”

“… 13 All the studies specifically included patients with COVID-19, but three studies also reported data on historical cohorts of non COVID-19 patients. 15 , 19 , 21 …”

“… Male: 68% (49/72) Non-shockable: 83% (60/72) Shockable: 18% (12/72) 30-day mortality: 75% (54/72) ROSC: 31% (22/72) 13/16 Thapa et al (2021) 20 Single centre retrospective study (US) Both ICU and non-ICU 54 hospitalized patients with COVID-19 who developed IHCA and received CPR ICU: 18.5% (10/54) Age: 61 y.o. (IQR 50-68) Male: 61% (33/54) On vasopressors: 46% (25/54) On MV: 79% (43/54) Non-shockable: 96% (52/54) Shockable: 4% (2/54) In-hospital mortality: 100% (54/54) ROSC: 54% (29/54) 12/16 Yuriditsky et al (2020) 15 Single centre retrospective observational study (US) Both ICU and non-ICU 55 hospitalized patients with COVID-19 (PCR testing) who developed IHCA and received CPR ICU: 83.6% (46/55) Age: 69 y.o. (IQR 64-77) Male: 87% (48/55) On vasopressors/inotropes: 67% (37/55) On IMV: 76% (42/55) Non-shockable: 89% (49/55) Shockable: 11% (6/55) 30-day mortality: 80% (44/55) ROSC: 38% (21/55) Favorable c neurological status at 30 day: 9% (5/55) 13/16 The table shows the main characteristics of the included studies, as reported by the authors, and the qualitative assessment performed using the MINORS tool.…”

“…Six studies had 13/16 as overall qualitative assessment score, 5 , 14 , 15 , 16 , 19 , 21 three studies had 12/16 17 , 18 , 20 and one had 14/16. 13 The detailed qualitative assessment with individual domain score per study is provided as Table S3, Supplementary material 2.…”

“…Seven studies provided data on the rate of IHCA with attempted CPR in cohorts of hospitalized patients with COVID-19, 5 , 13 , 14 , 15 , 18 , 20 with an estimated overall rate of IHCA of 4.1% (95% P.I. 2.1%-7.8%; 816/17028 patients; I 2 = 99%; Fig.…”