Clinical characteristics and outcomes of acute coronary syndrome patients with left anterior hemiblock

Zhang, Hanfei; Goodman, Shaun G.; Steg, Philippe Gabriel; Budaj, Andrzej; López‐Sendón, José; Dorian, Paul; Huynh, Thao; Mangat, Iqwal; Wong, Graham C.; Spencer, Frederick A.; Yan, Andrew T.

doi:10.1136/heartjnl-2014-305708

Cited by 4 publications

(3 citation statements)

References 32 publications

(29 reference statements)

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“…It is now well known that QT and QTc prolongation causes life-threatening arrhythmias, and it has also started to be realized that LAH is important regarding cardiac comorbidities. In studies previously conducted, LAH has been found to be associated with increased cardiac death in patients with suspicion of CAD and increased mortality in the hospital and during the 6-monthfollow up in patients with acute coronary syndrome (16,17). Hence, in patients with leprosy, in addition toQT and QTc prolongation, LAH that occurs at high rates is also an important ECG finding that should be considered, and it is highly important to monitor the QT and QTc intervals on ECG to predict arrhythmic events in these patients.…”

Section: Discussionmentioning

confidence: 99%

Electrocardiographic Findings of Leprosy

Yıldırım¹,

Seçen²,

Demir³

et al. 2018

Erciyes Med J

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Objective: The purpose of the present study was to investigate the effect of leprosy on basic electrocardiography (ECG) parameters. Materials and Methods: A total of 66 patients including 33 patients with leprosy (mean age: 70.06 years, 24 males) and 33 control patients (mean age: 56.66 years, 15 males) were included in the study. ECG recordings of all patients were obtained, and groups were compared in terms of heart rate, PR, QT, QTc, JTc, and T peak to T end (Tp-e) durations and branch blocks. Results: QT (391.30 vs. 367.66, p<0.01), QTc (423.57 vs. 407.15, p<0.01), and Tp-e (74.18 vs. 66.93, p<0.001) intervals were significantly prolonged in the leprosy group. The left anterior hemiblock (LAH) was observed more in patients with leprosy (42.4% in 14 patients) than in the non-leprosy group (42.4% vs. 12.1%, p<0.01). In addition, the rate of the unifascicularblock was significantly higher in the leprosy group (39.4% vs. 9.1%, p<0.01). Conclusion: Leprosy has a significant effect on QT, QTc, and Tp-e intervals. Prolongation of the QT, QTc, and Tp-e intervals is an indicator of leprosy's effect on the cardiac autonomic system. The ratio of the LAH is also rather high, and that may be a marker of the area where leprosy is most effective on the heart.

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Section: Discussionmentioning

confidence: 99%

Electrocardiographic Findings of Leprosy

Yıldırım¹,

Seçen²,

Demir³

et al. 2018

Erciyes Med J

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“…18,19) In contrast, some studies have mentioned that the development of left axis deviation in AMI is associated with a good prognosis, and this supports our result. [20][21][22] Kim, et al also demonstrated that postprocedural TIMI flow in non-ST-elevation myocardial infarction patients did not affect the clinical outcomes. 23) However, here, the patient had a potential possibility to implant a permanent pacemaker.…”

Section: Discussionmentioning

confidence: 99%

Rescue Percutaneous Coronary Intervention for a Lethal "Jailed" Septal Perforator Branch to Resolve Delayed Complete Atrioventricular Block

et al. 2019

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Delayed complete atrioventricular (AV) block associated with an occluded septal perforator branch (SPB) is an uncommon complication after performing percutaneous coronary intervention (PCI) for the left anterior descending coronary artery (LAD). Here we report the case of a 74-year-old man who underwent elective PCI for proximal LAD complicated with occlusion of the first major SPB and developed a complete AV block 78 hours after PCI was performed. The patient received a temporary transvenous pacemaker via the jugular vein and successfully underwent balloon angioplasty of the lethal "jailed" SPB, resulting in recovery from the complete AV block. Permanent pacemaker implantation was avoided. Our findings indicate the importance of postprocedural monitoring and consideration of rescue PCI for an occluded SPB in cases of complicated AV conduction disturbances.(Int Heart J 2019; 60: 457-461)

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“…Zhang et al report in this issue,1 in their comparison of quality of care and outcomes of patients with left anterior hemiblock (LAHB) hospitalised with acute coronary syndrome (ACS), lower rates of coronary revascularisation and reperfusion and higher rates of in-hospital and 6-month unadjusted mortality. They suggest that the more conservative approach to ACS care is due to the coexistence of comorbidities in patients with LAHB.…”

mentioning

confidence: 99%

Inferior quality of care and outcomes for acute coronary syndrome with left anterior hemiblock

Gale

2014

Heart

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Clinical characteristics and outcomes of acute coronary syndrome patients with left anterior hemiblock

Cited by 4 publications

References 32 publications

Electrocardiographic Findings of Leprosy

Electrocardiographic Findings of Leprosy

Rescue Percutaneous Coronary Intervention for a Lethal "Jailed" Septal Perforator Branch to Resolve Delayed Complete Atrioventricular Block

Inferior quality of care and outcomes for acute coronary syndrome with left anterior hemiblock

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