Clinical Characteristics and Management of Patients With Concomitant Liver Cirrhosis and Lymphoma: A Systematic Review

Jelicic, Jelena; Larsen, Thomas Stauffer; Fialla, Annette Dam; Bukumirić, Zoran; Andjelic, Bosko

doi:10.1016/j.clml.2022.07.006

Cited by 1 publication

(2 citation statements)

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“…Large B‐cell lymphoma has an incidence of 5–7 cases per 100,000 cases per year in the general population, but cases of DLBCL with cirrhosis are much rarer 4,5 . In previous studies of patients with lymphoma and cirrhosis, 62.6% had HCV‐related cirrhosis, 13.5% had HBV‐related cirrhosis, and 7.8% had alcohol‐related liver disease 6 . Moreover, a large retrospective study from a tertiary care center in Mexico found that the most frequent etiology of cirrhosis in patients with lymphoma was HCV (detected in 50% of cases).…”

Section: Discussionmentioning

confidence: 99%

“… 4 , 5 In previous studies of patients with lymphoma and cirrhosis, 62.6% had HCV‐related cirrhosis, 13.5% had HBV‐related cirrhosis, and 7.8% had alcohol‐related liver disease. 6 Moreover, a large retrospective study from a tertiary care center in Mexico found that the most frequent etiology of cirrhosis in patients with lymphoma was HCV (detected in 50% of cases). Ninety percent of these patients had NHL and the most common type was DLBCL with a high International Prognostic Index value.…”

Section: Discussionmentioning

confidence: 99%

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A case of diffuse large B‐cell lymphoma with decompensated alcohol‐related liver cirrhosis treated successfully by chemoimmunotherapy

Li,

Kong

2024

Clinical Case Reports

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Key Clinical MessageThis report describes a case of diffuse large B‐cell lymphoma with MYD88 L265P and KM2DT mutation and decompensated alcohol‐related liver cirrhosis. And the treatment is successful in this patient, who had multiple complications and poor prognostic factors.AbstractThis report describes a case of diffuse large B‐cell lymphoma with MYD88 L265P and KM2DT mutation and decompensated alcohol‐related liver cirrhosis. The lymphoma showed a complete response with no MYD88 L265P mutation after four courses of combination chemotherapy. Lymphoma is one of the most common malignant tumors, but cases of DLBCL with cirrhosis are much rarer especially with alcohol‐related cirrhosis. And we reviewed the relevant mechanisms. Although we did not find a definite association between the pathogenesis of the patient's alcohol‐related cirrhosis and that of diffuse large B‐cell lymphoma, the treatment is successful in this patient, who had multiple complications and poor prognostic factors.

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Section: Discussionmentioning

confidence: 99%