Clinical characteristics and factors associated with COVID-19-related death and morbidity among hospitalized patients with cancer: a Swedish cohort study

Ullgren, Helena; Camuto, Angela; Rosas, Sumy; Pahnke, Simon; Ginman, Beatrice; Enblad, Gunilla; Glimelius, Ingrid; Fransson, Per; Friesland, Signe; Liu, Lisa L.

doi:10.1080/0284186x.2021.1958005

Cited by 3 publications

(2 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Older age leads to a deficiency in the immune response, resulting in a higher risk of death in COVID-19 patients [ 41 ]. The strength and direction of the association between age and COVID-19 mortality have been consistently found across multiple studies [ 10 – 12 , 27 , 29 – 32 , 38 – 40 ].…”

Section: Discussionmentioning

confidence: 81%

“…In our study, we observed this association, although it was not significant. Findings in this regard are contradictory; some studies have found it to be a risk factor for death in COVID-19 [ 10 , 11 , 27 , 32 ], while others have not [ 12 , 38 – 40 ]. In contrast, the non-association between the type of cancer, solid tumor or hematological neoplasm, and the probability of death in COVID-19 patients coincides with several studies [ 10 – 12 , 27 , 30 – 32 , 39 ].…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Active cancer as the main predictor of mortality for COVID-19 in oncology patients in a specialized center

Villanueva-Cotrina,

Velarde,

Rodriguez

et al. 2023

Pathol. Oncol. Res.

View full text Add to dashboard Cite

Introduction: The role of the type, stage and status of cancer in the outcome of COVID-19 remains unclear. Moreover, the characteristic pathological changes of severe COVID-19 reveled by laboratory and radiological findings are similar to those due to the development of cancer itself and antineoplastic therapies.Objective: To identify potential predictors of mortality of COVID-19 in cancer patients.Materials and methods: A retrospective and cross-sectional study was carried out in patients with clinical suspicion of COVID-19 who were confirmed for COVID-19 diagnosis by RT-PCR testing at the National Institute of Neoplastic Diseases between April and December 2020. Demographic, clinical, laboratory and radiological data were analyzed. Statistical analyses included area under the curve and univariate and multivariate logistic regression analyses.Results: A total of 226 patients had clinical suspicion of COVID-19, the diagnosis was confirmed in 177 (78.3%), and 70/177 (39.5%) died. Age, active cancer, leukocyte count ≥12.8 × 109/L, urea ≥7.4 mmol/L, ferritin ≥1,640, lactate ≥2.0 mmol/L, and lung involvement ≥35% were found to be independent predictors of COVID-19 mortality.Conclusion: Active cancer represents the main prognosis factor of death, while the role of cancer stage and type is unclear. Chest CT is a useful tool in the prognosis of death from COVID-19 in cancer patients. It is a challenge to establish the prognostic utility of laboratory markers as their altered values it could have either oncological or pandemic origins.

show abstract

Section: Discussionmentioning

confidence: 81%

Section: Discussionmentioning

confidence: 99%

Active cancer as the main predictor of mortality for COVID-19 in oncology patients in a specialized center

Villanueva-Cotrina,

Velarde,

Rodriguez

et al. 2023

Pathol. Oncol. Res.

View full text Add to dashboard Cite

show abstract

Strict self-isolation did not protect Swedish cancer patients on active treatment from the risk of becoming seropositive for SARS-CoV-2

Ginman,

Pahnke,

Freyhult

et al. 2023

Acta Oncologica

View full text Add to dashboard Cite

Features of course and prevalence of COVID-19 among cancer patients in different countries

Yuldasheva,

Sakaeva,

Kunafia

2023

Medicinskij alfavit

View full text Add to dashboard Cite

Relevance. SARS-CoV-2 and the disease it caused, COVID-19, became the reason of pandemic that changed the entire life of mankind once and for all. In the fist months, due to the lack of reliable data on this virus, experts could not even imagine how this situation would affect cancer patients. With the accumulation of experience in working with these patients in the conditions of the COVID-19 pandemic, articles summarizing information about the incidence of new coronavirus infection (NCI) and its course in cancer patients began to appear in medical publications. Up-to-date information on this topic is presented in this review.Target. The study of the prevalence and features of the course of COVID-19 based on the analysis of current scientifi publications on this topic.Results. The course of COVID-19 depends on many factors, including age, gender, comorbidity, ECOG status, recent cytotoxic chemotherapy, and the type of solid tumor.Conclusions. Due to the absence of a register of the incidence of COVID-19 in Russia, cancer patients do not have a complete understanding of how the tumor process proceeds after recovery from NCI. This requires further research and in-depth analysis.

show abstract

Clinical characteristics and factors associated with COVID-19-related death and morbidity among hospitalized patients with cancer: a Swedish cohort study

Cited by 3 publications

References 27 publications

Active cancer as the main predictor of mortality for COVID-19 in oncology patients in a specialized center

Active cancer as the main predictor of mortality for COVID-19 in oncology patients in a specialized center

Strict self-isolation did not protect Swedish cancer patients on active treatment from the risk of becoming seropositive for SARS-CoV-2

Features of course and prevalence of COVID-19 among cancer patients in different countries

Contact Info

Product

Resources

About