Clinical Characteristics and Durations of Hospitalized Patients with COVID-19 in Beijing: A Retrospective Cohort Study

Zhao, Wen; Zha, Xiangyi; Wang, Ning; Li, Dongzeng; Li, Aixin; Yu, Shijie

doi:10.15212/cvia.2021.0019

Cited by 17 publications

(30 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Likewise, a Chinese study represented that bilateral pneumonia in a lung CT scan, a short period from symptoms onset to hospitalization, lymphopenia, and disease severity were the main factors in prolonged LOS (ProLOS). 44 Limitations of this study include the lack of accessibility to the molecular kit at the beginning of the pandemic. Therefore molecular confirmation of COVID-19 was impossible for all included patients.…”

Section: Resultsmentioning

confidence: 99%

“…29 Chinese research explained that bilateral pneumonia, shorter duration of onset to admission, lymphopenia, and disease severity are regarded as risk factors of prolonged hospitalization of COVID-19. 30 Lymphopenia may occur along with an increased level of cytokine, disease severity, mortality, and impaired immune response. 31 Tan et al 32 showed the inverse relationship between lymphocyte count and disease severity and its prognosis in 92 COVID-19 patients.…”

Section: Resultsmentioning

confidence: 99%

“…A study done on 221 hospitalized COVID‐19 patients confirmed leukopenia (33%), lymphopenia (73.8%), and more susceptibility to fungal and bacterial infections 29 . Chinese research explained that bilateral pneumonia, shorter duration of onset to admission, lymphopenia, and disease severity are regarded as risk factors of prolonged hospitalization of COVID‐19 30 . Lymphopenia may occur along with an increased level of cytokine, disease severity, mortality, and impaired immune response 31 …”

Section: Discussionmentioning

confidence: 98%

See 2 more Smart Citations

Lymphopenia and lung complications in patients with coronavirus disease‐2019 (COVID‐19): A retrospective study based on clinical data

Zaboli

Majidi

Alizadeh‐Navaei

et al. 2021

Journal of Medical Virology

View full text Add to dashboard Cite

A rapid outbreak of novel coronavirus, coronavirus disease‐2019 (COVID‐19), has made it a global pandemic. This study focused on the possible association between lymphopenia and computed tomography (CT) scan features and COVID‐19 patient mortality. The clinical data of 596 COVID‐19 patients were collected from February 2020 to September 2020. The patients' serological survey and CT scan features were retrospectively explored. The median age of the patients was 56.7 ± 16.4 years old. Lung involvement was more than 50% in 214 COVID‐19 patients (35.9%). The average blood lymphocyte percentage was 20.35 ± 10.16 (normal range, 20%–50%). Although the levels of C‐reactive protein (CRP) and erythrocyte sedimentation rate (ESR) were high in more than 80% of COVID‐19 patients; CRP, ESR, and platelet‐to‐lymphocyte ratio (PLR) may not indicate the in‐hospital mortality of COVID‐19. Patients with severe lung involvement and lymphopenia were found to be significantly associated with increased odds of death (odds ratio, 9.24; 95% confidence interval, 4.32–19.78). These results indicated that lymphopenia < 20% along with pulmonary involvement >50% impose a multiplicative effect on the risk of mortality. The in‐hospital mortality rate of this group was significantly higher than other COVID‐19 hospitalized cases. Furthermore, they meaningfully experienced a prolonged stay in the hospital ( p = .00). Lymphocyte count less than 20% and chest CT scan findings with more than 50% involvement might be related to the patient's mortality. These could act as laboratory and clinical indicators of disease severity, mortality, and outcome.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 98%

See 1 more Smart Citation

Lymphopenia and lung complications in patients with coronavirus disease‐2019 (COVID‐19): A retrospective study based on clinical data

Zaboli

Majidi

Alizadeh‐Navaei

et al. 2021

Journal of Medical Virology

View full text Add to dashboard Cite

show abstract

“…All studies were conducted between January 2020 and June 2020: 7 in January, 112 in February, 50 in March, 28 in April, 15 in May, and 3 in June. Seventeen preprint studies (Chen et al, 2020a, 2020b; Duan et al, 2020; Fu et al, 2020; Kuang et al, 2020; Li et al, 2020; Liu et al, 2020; Nie et al, 2020; Qi et al, 2020a, 2020b; Qin et al, 2020; Shi et al, 2020; Song et al, 2020; Tao et al, 2020; Wen et al, 2020; Xu et al, 2020; Zhao et al, 2020) were included in the analysis. All the studies included in this meta-analysis were of retrospective design.…”

Section: Resultsmentioning

confidence: 99%

Clinical Features of COVID-19 Patients in the First Year of Pandemic: A Systematic Review and Meta-Analysis

Maqbali

Albadi

Sinani

et al. 2021

Biological Research For Nursing

View full text Add to dashboard Cite

Background The new coronavirus disease (COVID-19) carries a high risk of infection and has spread rapidly around the world. However, there are limited data about the clinical symptoms globally. The purpose of this systematic review and meta-analysis is to identify the prevalence of the clinical symptoms of patient with COVID-19. Methods A systematic review and meta-analysis were carried out. The following databases were searched: PubMed, CINAHL, MEDLINE, EMBASE, PsycINFO, medRxiv, and Google Scholar, from December 1st, 2019 to January 1st, 2021. Prevalence rates were pooled with meta-analysis using a random-effects model. Heterogeneity was tested using I-squared (I2) statistics. Results A total of 215 studies, involving 132,647 COVID-19 patients, met the inclusion criteria. The pooled prevalence of the four most common symptoms were fever 76.2% ( n = 214; 95% CI 73.9–78.5); coughing 60.4% ( n = 215; 95% CI 58.6–62.1); fatigue 33.6% ( n = 175; 95% CI 31.2–36.1); and dyspnea 26.2% ( n = 195; 95% CI 24.1–28.5). Other symptoms from highest to lowest in terms of prevalence include expectorant (22.2%), anorexia (21.6%), myalgias (17.5%), chills (15%), sore throat (14.1%), headache (11.7%), nausea or vomiting (8.7%), rhinorrhea (8.2%), and hemoptysis (3.3%). In subgroup analyses by continent, it was found that four symptoms have a slight prevalence variation—fever, coughing, fatigue, and diarrhea. Conclusion This meta-analysis found the most prevalent symptoms of COVID-19 patients were fever, coughing, fatigue, and dyspnea. This knowledge might be beneficial for the effective treatment and control of the COVID-19 outbreak. Additional studies are required to distinguish between symptoms during and after, in patients with COVID-19.

show abstract

“…[ 2 ] The virus, owing to its high infectivity, spreads quickly and widely, and its numbers are still increasing. [ 3 ]…”

mentioning

confidence: 99%

Transient myopia due to choroidal effusion: A novel ocular complication of COVID-19 infection

Deori

Garg

Bhattacharjee

et al. 2021

Indian Journal of Ophthalmology

View full text Add to dashboard Cite

COVID-19 was declared as a global pandemic by the WHO in 2020. Although it is a respiratory virus, ocular complications and manifestations of the infection have been reported in different forms. We report a case of transient myopia and narrow angles due to choroidal effusion following infection by the SARS-COV-2 virus. We propose that the ability of the virus to incite an inflammatory response in the host body may be the mechanism behind the disease entity. This is a novel, previously undocumented ocular complication in case of a COVID-19 infection.

show abstract

Clinical Characteristics and Durations of Hospitalized Patients with COVID-19 in Beijing: A Retrospective Cohort Study

Cited by 17 publications

References 13 publications

Lymphopenia and lung complications in patients with coronavirus disease‐2019 (COVID‐19): A retrospective study based on clinical data

Lymphopenia and lung complications in patients with coronavirus disease‐2019 (COVID‐19): A retrospective study based on clinical data

Clinical Features of COVID-19 Patients in the First Year of Pandemic: A Systematic Review and Meta-Analysis

Transient myopia due to choroidal effusion: A novel ocular complication of COVID-19 infection

Contact Info

Product

Resources

About