Clinical assessment identifies hemodynamic profiles that predict outcomes in patients admitted with heart failure

Nohria, Anju; Tsang, Sui; Fang, James C.; Lewis, Eldrin F.; Jarcho, John A.; Mudge, Gilbert H.; Stevenson, Lynne Warner

doi:10.1016/s0735-1097(03)00309-7

Cited by 582 publications

(416 citation statements)

References 29 publications

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“…15 The significance of the serum T-Bil level depends on the type of HF, including disease severity and clinical stage; in other words, it is important to consider the HF status when the clinical significance of the serum T-Bil level is being evaluated.…”

Section: Clinical Impact Of Serum Bil Level On Hf Exacerbation In Relmentioning

confidence: 99%

Prognostic Significance of Increased Serum Bilirubin Levels Coincident With Cardiac Decompensation in Chronic Heart Failure

Shinagawa

Inomata

Koitabashi

et al. 2008

Circ J

103

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Section: Clinical Impact Of Serum Bil Level On Hf Exacerbation In Relmentioning

confidence: 99%

Prognostic Significance of Increased Serum Bilirubin Levels Coincident With Cardiac Decompensation in Chronic Heart Failure

Shinagawa

Inomata

Koitabashi

et al. 2008

Circ J

103

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“…In addition, ambulatory status (categorized as ambulatory, wheelchair [outdoor only], wheelchair [outdoor and indoor], or bedridden) will be evaluated at admission and at discharge. The type of clinical scenario (CS; 1,2,3,4,5)12 on admission, Nohria classification (warm & dry, warm & wet, cold & dry, or cold & wet)13, New York Heart Association functional classification (NYHA; I, II, III, VI)14 on admission and at discharge will be evaluated. The rate of dyspnoea relief at discharge will be evaluated by both patients and the attending physician using a seven‐level Likert‐scale.…”

Section: Methodsmentioning

confidence: 99%

Kyoto Congestive Heart Failure (KCHF) study: rationale and design

et al. 2017

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AimsOver the last decade, major developments in medicine have led to significant changes in the clinical management of heart failure patients. This study was designed to evaluate the recent trends in clinical characteristics, management, and short‐term and long‐term prognosis of patients with acute decompensated heart failure (ADHF) in Japan.Methods and resultsThe Kyoto Congestive Heart Failure study is a prospective, observational, multicentre cohort study, enrolling consecutive ADHF patients from 19 participating hospitals in Japan from November 2014 to March 2016. A total of 4000 patients will be enrolled into the study and patients' anthropometric, socio‐economic, and clinical data from hospital admission to discharge will be collected. In addition, in a pre‐determined subgroup of patients (n=1500), a longitudinal follow‐up for 2 years is scheduled.ConclusionsThe Kyoto Congestive Heart Failure study will provide valuable information regarding patients with ADHF in the real‐world clinical practice of Japan and will be indispensable for future clinical and policy decision‐making with respect to heart failure.

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“…Although these clinical profiles are based on the four haemodynamic Forrester classes, defined by pulmonary artery catheterization (pulmonary‐capillary wedge pressure ≤18 vs. >18 mmHg and cardiac index >2.2 vs. ≤2.2 L/min/m 2 ) with significant prognostic impact in patients with AMI,33 their ability to estimate prognosis is contradictory 34, 35, 36…”

Section: Vascular Phenotypes Of Acute Heart Failurementioning

confidence: 99%

Vascular phenotypes of acute decompensated vs. new‐onset heart failure: treatment implications

Ferreira

2017

ESC Heart Failure

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AimsAcute heart failure (HF) is a frequent and life‐threatening syndrome with heterogeneous clinical, haemodynamic, and neurohormonal features. This article describes the vascular phenotypes associated with acute decompensated chronic HF (ADCHF), and new‐onset acute HF (NOAHF).Data SynthesisWorsening of chronic HF occurs with full activation of adaptive mechanisms that maintain blood pressure (BP) and systemic perfusion. Rapid onset of HF in the setting of previous normal functioning heart not only does not allow full activation of adaptive mechanisms but also generates inappropriate responses from systemic endothelium leading to low BP/hypotension. Consequently, the treatment of ADCHF is based on diuretics and vasodilators, while in NOAHF, vasoconstrictors may be required to maintain BP to allow the correction of the acute cardiac disease.ConclusionsPatients with ADCHF and NOAHF present different vascular phenotypes with treatment implications.

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Clinical assessment identifies hemodynamic profiles that predict outcomes in patients admitted with heart failure

Abstract: Simple clinical assessment can be used to define profiles in patients admitted with HF. These profiles predict outcomes and may be used to guide therapy and identify populations for future investigation.

Cited by 582 publications

References 29 publications

Prognostic Significance of Increased Serum Bilirubin Levels Coincident With Cardiac Decompensation in Chronic Heart Failure

Prognostic Significance of Increased Serum Bilirubin Levels Coincident With Cardiac Decompensation in Chronic Heart Failure

Kyoto Congestive Heart Failure (KCHF) study: rationale and design

Vascular phenotypes of acute decompensated vs. new‐onset heart failure: treatment implications

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