Clinical Aspects of Penicillin Failure in Gonorrhoea

Consumption of antibiotics in Greenland, 1964-70. 3. Effect of coincidental administration of antibiotics on gonorrhoeal infections.

“…However, the choice of a suitable concentration and duration depends on the extent and duration of the infection, and particularly on the sensitivity of the infecting strain to the drug used. Wray (1965) found that there were almost twice as many failures as successes in men with gonococcal symptoms of more than 6 or 7 days' duration. Possibly because gonorrhoea in females is generally diagnosed later in the course of the infection than in males (Nicol, 1948;Nexmand, 1961;Ekstr6m, 1972), the cure rate is often lower in women than in men.…”