Clinical Aspects of Guillain-Barré Syndrome: A Review

Abstract

and Strohl published an account of two soldiers, whose nonfatal ascending paralytic illness was similar in many respects to that described in numerous previous publications (see Haymaker & Kernohan 1949), there was already an extensive literature of cases of ascending flaccid paralysis with sensory symptoms. Landry (1859) reviewed 10 patients with a fatal form of ascending paralysis, some with facial paralysis, but Guillain and his colleagues did not accept these as examples of polyradiculoneuritis because oftheir fatal outcome (Guillain et al. 1916, Guillain 1936a). Guillain (1936a, b) was particularly strict in his definition of the syndrome; for example, he preferred to exclude all cases with a fatal outcome, with a febrile onset, with central manifestations, and with a cerebrospinal fluid

A Child with Benign Acute Childhood Myositis After Influenza

“…Findings not classically associated with BACM include myoglobinuria, recent trauma or vigorous exercise, a family history of neuromuscular disorders, a sub-acute or chronic progression, a new rash, or any frank muscle weakness or abnormal neurological findings. When such atypical features are present, an alternative disorder such as rhabdomyolysis, GuillainBarré syndrome, dermatomyositis, polymyositis, or muscular dystrophy must be considered (12)(13)(14)(15). Consideration and exclusion of these other conditions is critical during both the evaluation and disposition of the pediatric patient with lower extremity muscle pain and possible weakness (Table 2).…”