Clinical Aspects of Congenital Tuberculosis

A rare case of facial palsy caused by Tuberculosis in 1 month old infant

“…Although the reported incidence of Neonatal TB is low [8], it is generally a serious condition with a mortality rate of 22% despite treatment [3,9,10]. The clinical presentation of neonatal tuberculosis has a peak onset three to four weeks after delivery but has been reported during the first week of life [7].…”

Congenital tuberculosis complicated by interstitial pulmonary emphysema

“…[1] In spite of high incidence of tuberculosis and its sub-clinical forms in women of reproductive age group in developing countries, congenital tuberculosis is a rare disease with mortality rate of 22%. The probable reason for the rarity may be under-reporting of the disease and lack of good diagnostic tools.…”

Congenital Tuberculosis in an Infant – Epidemiological Investigation

“…The clinical features of congenital TB have been described by Hudson (1956). 6 Cantwell et al 7 have proposed revised diagnostic criteria for the diagnosis of congenital TB.…”

“…6 Cantwell et al 7 have proposed revised diagnostic criteria for the diagnosis of congenital TB. The infant must have proved tuberculous lesions and at least one of the following: (i) Lesions in the first week of life; (ii) A primary hepatic complex or caseating hepatic granulomas (iii) Tuberculous infection of the placenta or the maternal genital tract or (iv) Exclusion of the possibility of postnatal transmission by a thorough investigation of contacts, including the infant's hospital attendants and by adherence to existing recommendations for treating infants exposed to tuberculosis.…”