2020
DOI: 10.1016/j.mpaic.2019.10.015
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Clinical approach to comatose patients

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Cited by 3 publications
(4 citation statements)
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“…Rhabdomyolysis can result from prolonged coma; conversely, certain conditions that can cause rhabdomyolysis may result in coma. [13][14][15] Thus, we suggest that serum creatine kinase should be included as part of the initial workup for acutely unconscious patients when a reliable history cannot be obtained from the patient or any informant. To illustrate the relationship between elevated serum creatine kinase levels and coma, we created a diagram, as shown in Figure 2.…”
Section: Discussionmentioning
confidence: 99%
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“…Rhabdomyolysis can result from prolonged coma; conversely, certain conditions that can cause rhabdomyolysis may result in coma. [13][14][15] Thus, we suggest that serum creatine kinase should be included as part of the initial workup for acutely unconscious patients when a reliable history cannot be obtained from the patient or any informant. To illustrate the relationship between elevated serum creatine kinase levels and coma, we created a diagram, as shown in Figure 2.…”
Section: Discussionmentioning
confidence: 99%
“…Careful systematic and targeted clinical examinations from head to toe are essential. [ 13 , 14 ] In view of the broad differential diagnoses for unconsciousness, some basic initial screening blood investigations may be useful to guide further investigation or management.…”
Section: Discussionmentioning
confidence: 99%
“…Furthermore, vital and functional prognoses are largely influenced by the cause of the coma [ 24 , 25 ]. Several classifications of the etiologies of NTC exist; however, the distinction between primary (or structural) and systemic (non-structural or diffuse) causes based on whether a structural local lesion exists in the brain is one of the most widely used classifications [ 9 , 20 ].…”
Section: Discussionmentioning
confidence: 99%
“…Based on clinical, biological, and brain imaging information, the causes/etiologies of coma are divided into structural or primary brain disorders (stroke, meningoencephalitis, or brain tumors, among others) and non-structural or systemic disorders (medical conditions that secondarily cause diffuse brain dysfunction such as metabolic disturbances, septic shock, or hypertensive hypertension, among others) [ 20 ].…”
Section: Methodsmentioning
confidence: 99%